Among the molds causing allergy, Aspergillus fumigatus (Af) constituted a major species present both indoors and outdoors. The antigens both secreted and bound to hyphae and conidia have been isolated for immunodiagnosis of allergic aspergillosis. The crude extracts have been used to demonstrate IgE antibody in vitro and for skin testing. The crude extracts contain many antigenic and non-antige...

Comments on ''Detection of galactomannan in the bronchoalveolar lavage of high-risk patients with invasive aspergillosis admitted at the intensive care unit'' by Khodavaisy et al.  AWT-SEP    AWT-SEP    AWT-SEP    AWT-SEP    AWT-SEP    AWT-SEP  Galactomannan in bronchoalveolar lavage for diagnosis of invasive aspergillosis  We rea...

BACKGROUND Fungal sensitization is common in severe asthma, but the clinical relevance of this and the relationship with airway colonization by fungi remain unclear. The range of fungi that may colonize the airways in asthma is unknown. OBJECTIVE To provide a comprehensive analysis on the range of filamentous fungi isolated in sputum from people with asthma and report the relationship with th...

BACKGROUND The enzyme linked immunosorbent assay (ELISA) for detecting IgG antibodies to Aspergillus fumigatus is more sensitive than the measurement of Aspergillus precipitins. The relation of the results from both techniques to the clinical pattern of disease in a large unselected group of patients from a large referral centre is unknown. METHODS The clinical relation of precipitins to Aspe...

BACKGROUND The study objectives were: 1) to report on invasive aspergillosis patients in a hematology department; and 2) to estimate its incidence according to the hematologic diagnosis. DESIGN AND METHODS A prospective survey of invasive aspergillosis cases was undertaken between January 2004 and December 2009 in the hematology department of a university hospital. Meetings with clinicians, m...

OBJECTIVES Fungal infections represent 5% of infections in renal transplant recipients. Candidiasis is the most frequent, followed by aspergillosis and cryptococcosis. Invasive aspergillosis is severe and has a poor prognosis, but recent series focused on outcomes are scarce in the literature. We analyzed invasive aspergillosis cases in a cohort of kidney transplant recipients and suggest that ...

Tracheobronchial aspergillosis mainly involves the trachea, primary bronchus and segmental bronchus. the main symptoms including dyspnea, asthma and cough [1]. Based on clinical, bronchoscopic, and pathological presentations, Kramer and coworkers proposed a classification of tracheobronchial aspergillosis, they distinguished saprophytic, allergic, and invasive tracheobronchial aspergillosis (IT...

ASPERGILLOSIS IN CLINICAL CONTEXT Aspergillosis is a fungal infection that can assume a broad spectrum of clinical forms depending on immune status and the presence of underlying lung diseases, ranging from allergic bronchopulmonary aspergillosis to aspergilloma and also to the invasive aspergillosis forms that are a major cause of mortality in severely immunocompromised patients. Pulmonary asp...

The authors report four autopsy cases of previously healthy children with dengue shock syndrome complicated with infection-associated hemophagocytosis and invasive aspergillosis. Hemophagocytosis is confirmed by histopathology of autopsied reticuloendothelial organs. All four children were identified to have invasive aspergillosis by histopathology and three cases were positive on fungal cultur...

lipoid proteinosis (lp) is a rare autosomal recessive disease characterized by the deposition of an amorphous hyaline material in the skin, mucosa and viscera. the classic manifestation is onset in infancy with a hoarse cry due to laryngeal infiltration. skin and mucous changes develope, and the disease follows a slowly progressive course. in this case report, a 49 year-old man presented with a...