The cholesteryl-ester transfer protein (CETP) facilitates the transfer of cholesterol esters and triglycerides between lipoproteins in plasma where the critical site for its function is situated in the C-terminal domain. Our group has previously shown that this domain presents conformational changes in a non-lipid environment when the mutation D(470)N is introduced. Using a series of peptides d...

blood transfusion centers are under considerable pressure to produce platelet concentrates with a shelf life limit of 3 to 5 days. many approaches have been investigated experimentally to produce new hemostatically active platelet products that are capable of long term storage. in this article infusible platelet membrane will be explained as a platelet substitute versus conventional liquid-stor...

PURPOSE In THA a sufficient primary implant stability is the precondition for successful secondary stability. Industrial foams of different densities have been used for primary stability investigations. The aim of this study was to analyse and compare the insertion behaviour of threaded and press-fit cups in vivo and ex vivo using bone substitutes with various densities. METHODS Two threaded ...