AIM Hypertriglyceridemia is the most common cause of low plasma high-density lipoprotein cholesterol (HDL-C) levels; however, the correlation between high triglyceride (TG) and low HDL-C remains unclear. Endothelial lipase (EL) is a determinant of plasma HDL levels. We investigated the role of EL in HDL metabolism in a murine model of acute hypertriglyceridemia. METHODS AND RESULTS To establi...

0022-1694/$ see front matter 2012 Elsevier B.V. A http://dx.doi.org/10.1016/j.jhydrol.2012.05.043 ⇑ Corresponding author. Tel.: +1 407 823 4843; fax E-mail addresses: [email protected] (S.C. Me (S.C. Hagen), [email protected] (J.F. Weisham 1 Tel.: +1 407 823 3903; fax: +1 407 823 3315. 2 Tel.: +1 407 823 6634; fax: +1 407 823 5769. Parameterizing surface roughness is a key element in th...

1Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei 112, Taiwan, 2Department of Neurosurgery, Taichung Veterans General Hospital, Taichung 407, Taiwan, 3Institute of Biomedical Sciences, National Chung Hsing University, Taichung 402, Taiwan, 4Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan, 5Department and In...

Subunit vaccines typically show insufficient immunogenicity. To address this issue, we developed a novel self-adjuvanting particulate carrier system based upon the lipids phytantriol (Phy) and mannide monooleate (MaMo). Phy is a lipid known to form nonlamellar phases in fully hydrated systems, whereas MaMo has been found to promote immune responses in emulsion form. A bulk phase composition of ...

The aims of this study were to prepare a thermosensitive composite hydrogel (TCH) by mixing 24% (w/v) poloxamer 407 (P407), 16% (w/v) poloxamer 188 (P188) and 0.1% (w/v) carbopol 940 (C940), and to determine the effect of natural borneol/ (2-hydroxypropyl)-β-cyclodextrin (NB/HP-β-CD) inclusion complex on the phase transition temperature, mechanical, rheological properties, and release behaviors...

Block copolymers are increasingly being applied in areas such as transfection, membrane sealing, site-specific targeting, and bionanoengineering yet there is a relative paucity of assays available for simple, stable and reproducible colorimetric determination of copolymer concentration in solution. We have focused on improving the accuracy and reproducibility of a modified version of the Stewar...

A β-glucosidase producing yeast strain was isolated from Korean traditional rice wine. Based on the sequence of the YCL008c gene and analysis of the fatty acid composition, the isolate was identified as Saccharomyces cerevisiae strain HJ-014. S. cerevisiae HJ-014 produced ginsenoside Rd, F2, and compound K from the ethanol extract of red ginseng. The production was increased by shaking culture,...

The objective of this work was to develop bioadhesive topical gel of Aceclofenac with the help of response-surface approach. Experiments were performed according to a 3-level factorial design to evaluate the effects of two independent variables [amount of Poloxamer 407 (PL-407 = X1) and hydroxypropylmethyl cellulose K100 M (HPMC = X2)] on the bioadhesive character of gel, rheological property o...

abduction [661]. abort [422]. abort-aware [422]. ABS [455]. Abstract [435, 620, 132, 419, 481, 425, 131, 122, 551]. Abstraction [597, 182, 489, 621, 323, 382, 123, 429, 359, 205, 326, 234, 407, 385, 325, 510, 40, 426]. abstraction-based [326, 325]. Abstraction-guided [489]. abstraction-refinement [407]. abstraction/refinement [359]. abstractions [406, 217, 618, 664, 321]. ABZ [642]. acceleratio...