The escape of anti-self B cells from tolerance mechanisms like clonal deletion, receptor editing, and anergy results in the production of autoantibodies, which is a hallmark of many autoimmune disorders. In this study, we demonstrate that both germline sequences and somatic mutations contribute to autospecificity of B cell clones. For this issue, we investigated the development of antinuclear a...

1 2 2 2 3 3 Thomas Pressel, Anas Bouguecha, Matthias Kammler, Bernd-Arno Behrens, Ute Vogt, Andrea Meyer-Lindenberg, 1 Henning Windhagen 1 Department of Orthopaedic Surgery, Hannover Medical School, Hannover, Germany; E-Mail: [email protected], 2 Institute of Metal Forming and Metal Forming Machines, University of Hannover, Hannover, Germany 3 Clinic for Small Domestic Animals, School of Vet...

Of six patients with rheumatoid arthritis (RA) treated with human recombinant interferon gamma for two to eight months, three developed antinuclear antibodies (ANAs). This was accompanied by a simultaneous clinical exacerbation of the disease activity. In this study both anti-inflammatory and immunostimulatory effects of human recombinant interferon gamma in patients with RA were observed.

An avian influenza virus strain, A/domestic green-winged teal/Hunan/2036/2007(H3N6) (DGW-T2036), was isolated from healthy domestic green-winged teals (Anas crecca) in Hunan Province, South China. All eight gene segments of the isolate were sequenced. Genomic analysis demonstrated that this H3N6 virus is a novel reassortant avian influenza virus with a gene constellation originating from multip...

Hematologic parameters were studied in giant Canada geese (Branta canadensis maxima), mallard ducks (Anas platyrhynchos platyrhynchos) and various species of diving ducks at seasinal intervals throughout the year. Highest values for packed cell volume, hemoglobin content and erythrocyte counts were found in the winter and pre-nesting periods. Mean corpuscular volume and mean corpuscular hemoglo...

Pattern of Pediatric Mortality in a Tertiary Hospital in Oman Mohamed El-Naggari, Anas-Alwogud Abdelmogheth, Hashim Javad, Khalfan Al Senaidi, and Ibtisam El Nour Department of Child Health, Sultan Qaboos University, Al-Khod 123, Sultanate of Oman Corresponding author: Dr. Mohamed El-Naggari, Department of Child Health, Sultan Qaboos University, Al-Khod 123, Sultanate of Oman. Tel: +968-9817823...

Here, we report the draft genome sequence of Enterococcus faecalis DBH18, a bacteriocinogenic lactic acid bacterium (LAB) isolated from mallard ducks (Anas platyrhynchos). The assembly contains 2,836,724 bp, with a G+C content of 37.6%. The genome is predicted to contain 2,654 coding DNA sequences (CDSs) and 50 RNAs.