OBJECTIVE To quantify more reliably the benefits and risks of monoamine oxidase type B inhibitors (MAOBIs) in early Parkinson's disease. DATA SOURCES Searches of the Cochrane Library, Medline, Embase, PubMed, and Web of Science for years 1966-2003, plus major journals in the field, abstract books, and proceedings of meetings, for randomised trials comparing MAOBIs with placebo or levodopa. ...

Cryptocurrencies (or digital tokens, digital currencies, e.g., BTC, ETH, XRP, NEO) have been rapidly gaining ground in use, value, and understanding among the public, bringing astonishing profits to investors. Unlike other money and banking systems, most digital tokens do not require central authorities. Being decentralized poses significant challenges for credit rating. Most ICOs are currently...

BACKGROUND Methods for describing one's confidence in the available evidence are useful for end-users of evidence reviews. Analysts inevitably make judgments about the quality, quantity consistency, robustness, and magnitude of effects observed in the studies identified. The subjectivity of these judgments in several areas underscores the need for transparency in judgments. DISCUSSION This pa...

A model was developed to estimate the medical costs and effectiveness outcomes of three antipsychotic treatments (olanzapine, haloperidol, and risperidone) for patients with schizophrenia. A decision analytic Markov model was used to determine the cost-effectiveness of treatments and outcomes that patients treated for schizophrenia may experience over a 5-year period. Model parameter estimates ...

Medium-ripe soybean varieties in the State Register of Plant Varieties Suitable for Distribution Ukraine 2021 are represented by 31 varieties. Drought resistance medium-ripe was 6–9 points. The most drought-resistant were Sandina, Panonka, ES Pallador, and least Valentia, KSB 938 – 6 points each, Poltava 7 seed yield is 18.0–34.6 c / ha. productive EC Pallador 34.6 с ha, Stein 14F06 34.1 17Zh32...

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The task of automated essay scoring (AES) continues to attract interdisciplinary attention due its commercial and educational importance as well related research challenges. Traditional AES approaches rely on handcrafted features, which are time-consuming labor-intensive. Neural network have recently given fantastic results in without feature engineering, but they usually require extensive anno...