Photodynamic Therapy (PDT) is a clinical procedure that is showing promising results in the treatment of certain types of cancer, including melanomas, oesophageal and retinal cancers [1-4]. The search for molecules suitable for use in PDT is a field of continuing interest. These molecules need to possess certain characteristics, including high affinity for tumour tissues and intense absorption ...

a novel potentiometric ion-selective pvc membrane sensor for analysis of atorvastatin (at) in pharmaceutical preparations based on atorvastatin-(tetraphenyl borate), (at-(tpb)2) as sensing element, tetraphenyl borate as additive and tris-2-ethyl-hexyl phosphate (top) as plasticizer solvent was prepared. the electrode shows a good nernestian response over the concentration range of 0.09–5586 µg ...

Protein; classification, structure and functions. Amino acids, Peptides and peptide bonds; essential and non-essential amino acids. Metabolism of amino acids: transamination, oxidative deamination, decarboxylation etc. urea cycle. Interconversions of threonine. In born errors of metabolism. Chemistry asnd structure of nucleic acids. Cataboliosm of purines, pyrimidines and nucleotides; disorders...

The artificial allosteric molecule, gable porphyrin metal complexes, were prepared by connecting two independent metal porphyrin molecules by covalent bond. The author would like to discuss mostly on allosteric mechanism of the artificial allosteric systems. Our gable porphyrin system behaves similarly to natural Hb, binding small molecules like CO, 02: or base, cooperatively. The original stru...

The photoinduced oxidation of tetra(N-methyl-4-pyridyl)porphyrinmanganese(III) has been achieved in homogeneous solution. The manganese porphyrin was used as an electron donor in a three-component system with tris-(2,2'-bipyridine)ruthenium(II) as the photosensitizer and chloropentaamminecobalt(III) as the electron acceptor. The photooxidized manganese porphyrin is unstable in aqueous solution,...

The photophysical properties of 2.3 nm thioglycolic acid (TGA) coated CdTe quantum dots (QDs) prepared by a reflux method have been studied in the presence of cationic meso-tetrakis(4-N-methylpyridyl) zinc porphyrin (ZnTMPyP4). Addition of the CdTe QDs to the porphyrin in H(2)O results in a marked red-shift and hypochromism in the porphyrin absorption spectrum, indicative of a non-covalent bind...