about 3 decades ago cd6 identified as one of the first antigens expresses on the majority of t cells and a subset of b cells. cd6 regulates cellular adhesion migration across the endothelial and epithelial cells. in recent years researches indicate its role in pathogenesis of autoimmune diseases. many researches have been done in recent years to block cd6 by cd6 mono clonal antibodies, ior-t1 a...

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tuberculose has increased in the recent years. use of a sensitive screening method, can be one of the influential parameters in reduction of pulmonary tuberculosis. current screening method in the laboratories is based on observation of bacilli in stained smear by ziel-neelsen procedure. the aim of this research was to study the pcr efficiency in all confirmed patients of hamadan province. twen...

background :   a  lot  of  studies  have  shown  periodontal  diseases  as  a  risk  factor  for  adverse  pregnancy  out­comes. the  as­sociation  between  periodontitis  and  preeclampsia  has  been  studied  recently  with  contro­versy. considering  the  importance  of  preventing  preeclampsia  as  a  dangerous  and  life-threatening  disease  in  pregnant  women,  the  pre­sent  study  wa...

coeliac disease (cd) is an autoimmune disorder which leads to chronic inflammation of the gut. untreated cd is associated with upper gastrointestinal malignancies, small-bowel lymphoma and adenocarcinoma are recognized complications of untreated coeliac disease (cd). we report the case of a 43-year-old male suffering from cd who was treated with a gluten-free diet one year,  presenting with com...

background despite improvements in medical care provided during pregnancy to diabetic mothers, the cardiac complications in their infants are still more frequent than in the infants of general population. conclusions our data showed a high prevalence of chd in idms in our pediatric cardiology clinic. neither the types of maternal diabetes nor the somatic findings of newborns were related to the...

dear editor-in-chief the recent report on “the adverse effects of pregnancies complicated by hemoglobin h (hbh) disease” is very interesting (1). rabiee et al. reported a pregnant case complicated with hbh disease. indeed, this problem might not common in the middle east but it is very common in southeast asia. the authors hereby would like to share the experience on this topic. in the recent r...

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background:â  northeastern iran has a high incidence for squamous cell esophageal carcinoma (escc). the aim of the study is to the assess relationship between celiac disease (cd) and escc. materials and methods:â  this was a two-part, cross-sectional, case-control study performed during 2006-2011 in gonbad, â golestan, iran. serum iga anti-tissue transglutaminase antibody levels were measured f...