Osteoarthritis (OA) is a prevalent chronic disease impacting on quality of life and has societal and economical burden increasing with age. Yet, no confirmed pharmacological, biological or surgical therapy could prevent the progressive destruction of OA joint. Mesenchymal stem cells (MSCs) with immunosuppressive activities emerged a potential therapy. We describe a magnetic resonance images (MR...

Suprascapular nerve blockade improves pain, range of motion, and disability in acute and chronic shoulder pain. Pain relief usually lasts several hours with local anesthetic. If steroids are added, the relief lasts several weeks. Since repetitive steroid exposure is associated with several hazards, alternative long-term therapies would be desirable. Pulsed mode radiofrequency is a non-destructi...

CLINICAL SCENARIO Low back pain is the most common type of pain reported by adults in the United States. A variety of manual therapy techniques are used in the management of low back pain to reduce pain, improve function, and reduce disability. In recent years, muscle energy techniques have been increasingly used in clinics to treat low back pain. By definition, a muscle energy technique involv...

background and objectives: continuous low back pain is obviously related to the symptoms of the pregnancy period. in spite of the spontaneous improvement of the pain in less than 6 months after the delivery, some women experience chronic problems. thus, the present study aimed to investigate the effect of dry cupping therapy at the bl23 point on the intensity of low back pain in the primiparous...

background: exercise is a widely prescribed treatment for chronic low back pain. the purpose of the present study was to investigate the effect of 8 weeks exercise on pain, disability and endurance of trunk flexor-extensor muscles in female with chronic idiopathic low back pain. methods: this clinical trial study has been done on 12 patients who referred to the arak city clinics. the function o...

the aim of this study was to evaluate the anti-nociceptive effects of a low, sub-effective dose of amitriptyline, in combination with the different doses of ethanolic and aqueous extracts of crocus sativus following sciatic nerve chronic constriction injury (cci) in rats. amitriptyline (3, 10 and 30 mg/kg, i.p.) and the extracts (25, 50 and 100 mg/kg, i.p.), were separately administered at the ...

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introduction: the american academy of orofacial pain defined temporomandibular disorders (tmds) as”a collective term that embraces a number of clinical problems that involve the masticatory muscles, the tmj (temporomandibular joint), and the associated structures”. pain and dysfunctional symptoms or signs such as limitations in opening, asymmetric jaw movements and tmj sounds are the most commo...

background postoperative pain is a common complication that can lead to serious morbidities and delayed recovery. objectives the aim of this study was to investigate the effect of low-level laser therapy on acute pain after tibial fracture surgery. patients and methods in this randomized clinical trial, 54 patients who were candidate for tibial fracture surgery were allocated randomly to two gr...