In this paper, we consider singular and degenerate parabolic equations$$u_t =(x^alpha u_x)_x +u^m (x_0,t)v^{n} (x_0,t),quadv_t =(x^beta v_x)_x +u^q (x_0,t)v^{p} (x_0,t),$$ in $(0,a)times (0,T)$, subject to nullDirichlet boundary conditions, where $m,n, p,qge 0$, $alpha, betain [0,2)$ and $x_0in (0,a)$. The optimal classification of non-simultaneous and simultaneous blow-up solutions is determin...