BACKGROUND Previous studies have shown that human epidermal growth factor receptor 2 (HER2) may play an important role in the invasion and metastasis of pancreatic cancer, but the relationship between HER2 amplification level and prognosis of pancreatic cancer patients is still controversial. Therefore, we performed a meta-analysis to determine the prognostic significance of HER2 amplification ...

For a separable metric space X, we consider possibilities for the sequence S(X) = {dn : n ∈ N} where dn = dimX. In Section 1, a general method for producing examples is given which can be used to realize many of the possible sequences. For example, there is Xn such that S(Xn) = {n, n + 1, n + 2, . . .}, Yn, for n > 1, such that S(Yn) = {n, n+ 1, n+ 2, n+ 2, n+ 2, . . .}, and Z such that S(Z) = ...

Machines whose sole function is to re-order their input data are considered. Every such machine defines a set of allowable input-output pairs of permutations. These sets are studied in terms of the minimal disallowed pairs (the basis). Some allowable sets with small bases are considered including the one defined by a priority queue machine. For more complex machines defined by two or more prior...

Aeroelastic flutter is a dangerous failure mode, and aircraft structural components are designed under a deterministic flutter margin. Meeting this safety factor may result in overly-conservative structures, however, an alternative approach incorporates uncertainties into the computational models, and imposes a maximum allowable flutter probability during the optimization process. This techniqu...

We describe a methodology to maximize slow-light pulse delay subject to a constraint on the allowable pulse distortion. We show that optimizing over a larger number of physical variables can increase the distortion-constrained delay. We demonstrate these concepts by comparing the optimum slow-light pulse delay achievable using a single Lorentzian gain line with that achievable using a pair of c...

In [8] we obtained stabilizing PID controllers for a class of MIMO unstable plants with time delays in the input and output channels (I/O delays). Using this approach, for plants with one unstable pole, we investigate resilient PI and PD controllers. Specifically, for PD controllers, optimal derivative action gain is determined to maximize the allowable controller gain interval. For PI controll...

Classical proper PID controllers are designed for linear time invariant plants whose transfer functions are rational functions of s , where 0 < α < 1, and s is the Laplace transform variable. Effect of input–output time delay on the range of allowable controller parameters is investigated. The allowable PID controller parameters are determined from a small gain type of argument used earlier for...

We report efficient amplification of weak femtosecond supercontinuum pulses by a stimulated Raman scattering process in pressurized H(2) gas excited with 350-fs-duration frequency-doubled pulses from a regenerativeamplified Ti:sapphire laser. An amplification factor of 10(9) is obtained at the wavelength of 465 nm for seed pulses produced by supercontinuum generation in glass.