computational tools are reliable alternatives to laborious work in chimeric protein design. in this study, a chimeric antigen was designed using computational techniques for simultaneous detection of anti-htlv-i and anti-hbv in infected sera. databases were searched for amino acid sequences of hbv/hlv-i diagnostic antigens. the immunodominant fragments were selected based on propensity scales. ...

background: new-onset atrial fibrillation (af) after cardiac surgery contributes to increased morbidity, hospital length of stay, and resource utilization. although many aspects of af after cardiac surgery have already been elucidated, the mechanism by which cardiac surgery predisposes patients to af has hitherto remained unknown. recent evidence supports the notion that blood transfusion enhan...

Erythropoietin combined with parenteral iron sucrose therapy is an alternative to blood transfusion in anemic patients. It was shown to be effective in surgical patients in several previous studies when used in conjunction with other methods. However, there are no guidelines about safety limits in dosage amounts or intervals. In this study, we report a case of significant postoperative hemorrha...

normal 0 false false false en-us x-none ar-sa background: hepatitis c virus (hcv) is the main causative agent of post-transfusion hepatitis. the virus is distributed worldwide with varying prevalence in different countries, which could easily lead to chronic infections, cirrhosis, and even hepatocellular carcinoma. the aim of this study was to investigate prevalence of hcv infection and its tre...

BACKGROUND Retransfusion of the patient's own blood during surgery is used to reduce the need for allogenic blood transfusion. It has however been found that this blood contains lipid particles, which form emboli in different organs if the blood is retransfused on the arterial side. In this study, we tested whether retransfusion of blood containing lipid micro-particles on the venous side in a ...

secondary prevention and high-risk primary prevention: rationale and design of the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management and Avoidance (CHARISMA). Am Heart J 2004;148:263–268. 35. Karabulut H, Toraman F, Evrenkaya S, Goksel O, Tarcan S, Alhan C. Clopidogrel does not increase bleeding and allogenic blood transfusion in coronary artery surgery. Eur J Ca...

background: to evaluate the present status of blood utilization and develop practice guidelines in teaching hospitals in northern iran. methods: we retrospectively analyzed the amount of blood prepared and used preoperatively for 11 elective procedures, from march 2010 to march 2011 in teaching hospitals in northern iran. study variables included the crossmatch transfusion ratio, the transfusio...

our previous studies on thalassemia patients, homozygous or compound heterozygous for severe beta thalassemia mutations, has suggested that 5’hs4-lcr and/or xmn1-hbg2 backgrounds, which were linked in our thalassemia patients, are important in determining the blood transfusion dependency of these individuals. while the majority of patients with aa/-- 5’hs4/xmn1 background, were severely depende...