BACKGROUND Liver cancer is a high incidence and fatal disease, the fifth most frequent cancer worldwide that is usually diagnosed at an advanced stage. The number of deaths from liver cancer has not declined even following various therapies. Plant secondary metabolites and their semi-synthetic derivatives play a principal role in anti-cancer drug therapy, since they are effective in the treatme...

BACKGROUND Hitherto available sources from literature mentioned several wild growing Allium species as "edible" or "medicinally used" but without any further specification. METHODS New data were gained during recent research missions: Allium plants were collected and shown to the local population which was asked for names and usage of these plants. RESULTS Information was collected about cu...

Due to the ease with which chromosomes can be observed, the Allium species, and onion in particular, have been familiar materials employed in cytogenetic experiments in biology. In this study, centromeric histone H3 (CENH3)-coding cDNAs were identified in four Allium species (onion, welsh onion, garlic and garlic chives) and cloned. Anti-CENH3 antibody was then raised against a deduced amino ac...

Plants of the Allium genus produce sulphur compounds that give them a characteristic (alliaceous) flavour and mediate for their medicinal use. In this study, the chemical composition and antimicrobial properties of Allium cepa red cv. and A. sativum in the context of three different drying processes were assessed using metabolomics. Bulbs were dried using either microwave, air drying, or freeze...

the effects of allium sativum on yogurt formation and subsequent storage (4°c, up to 28 days) on proteolysis, microbial activity, and inhibition of α-amylase, α-glucosidase and angiotensin-i converting enzymes were investigated in vitro. allium sativum yogurt showed higher rates of ph reduction and increment of titrable acid than control during the incubation at 41°c. highest proteolysis was ob...

A comparative study of the lectins from the families Amaryllidaceae and Alliaceae reveals many common features: all bind D-mannose exclusively and have similar molecular structures and amino acid compositions. All these lectins contain subunits of M, 11500-14000 which are not linked by disulphide bonds and occur as dimers (in Allium sativum, A. vineale, A. ursinum, A. moly, Narcissus pseudonarc...

Introduction: Allium cepa is a biological material of great importance for mutagenicity tests, due to the simplicity of its use in testing, the fast growth of its roots, and the response of genetic material to the presence of substances with cytotoxic and genotoxic potential. Method: The Allium test model by using the onion seed (Alium cepa L.) without the use of pesticides or any other chemica...

The effect of chemical mutagens on the induction of mitotic chromosomal aberrations in diploid Allium cepa and tetraploid Allium vineale has been studied. In inducing chromosomal aberrations in case of both diploid and tetraploid Allium all the mutagens were found to be effective . Mitotic irregularities were higher in tetraploid species as compared with the diploid species. All types of chemic...