Polymer nanocomposites containing nanometals became a subject of interest due to their bactericidal properties. Different polysaccharides have been used as matrices for nanosilver and nanogold synthesis. In this study, we present novel, environmentally friendly method the preparation sodium alginate/nanosilver/graphene oxide (GOX) alginate/nanogold/graphene GOX characteristics. The formation ap...

The aim of the study is to design octaarginine (R8)-modified insulin-alginate nanoparticles (INS-SA/R8 NPs) as oral insulin delivery system, and further investigate its penetrating mechanism. characterization results indicated that surface INS-SA/R8 NPs was smooth average diameter about 300 nm. exhibited a stronger stability in simulated gastrointestinal fluids had better controlled release tha...

Four hydrophilic polymers in the form of beads - chitosan, alginate, alginate/polyvinyl alcohol (PVA), and chitosan-coated alginate - were used as supports for lipase immobilisation. Hydrogel beads were characterised by bead-size-distribution estimation, surface morphology studies, and polymer interactions assessment. Matrix performances - loading efficiency, immobilisation yield, enzyme activi...

We describe a method for creating alginate hydrogels with adjustable degradation rates that can be used as scaffolds for stem cells. Alginate hydrogels have been widely tested as three-dimensional constructs for cell culture, cell carriers for implantation, and in tissue regeneration applications; however, alginate hydrogel implants can take months to disappear from implantation sites because m...

Simultaneous administration of different phenolic compounds might produce a synergistic effect offering greater activity against chronic non-communicable diseases. This has prompted significant interest in developing nanodelivery systems that simultaneously encapsulate bioactives and protect them from gastrointestinal digestion. work aimed at evaluating the suitability zein (ZN) zein/polysaccha...

The concurrent release of calcium phosphate and biomacromolecules may improve wound healing responses at the interface with ceramic materials of orthopaedic and dental implants. Hydrogel coatings consisting of a mixture of alginate and chitosan were doped and applied onto solid carriers with the aim of investigating their use as local delivery vehicles. Coatings containing both the model macrom...

Degenerative lumbar disease (DLD) is a significant issue for public health. Posterior lumbar intervertebral fusion with cages (PLIFC) has high-level fusion rate and realignment on DLD. However, there are some complications following the surgery. Alginate oligosaccharides (AOS) have antioxidant and anti-inflammatory activities and may be suitable for infection therapy. MiR-155 is a biomarker ass...

Nanotechnology also called as nanotech is referring to the science, technology and engineering synthesis, manipulation investigation of materials devices at nanoscales. Nanoparticles (NPs) owns a special place in nanotechnology due their extreme-small size, multifunctionality, modifiable surface for wide range applications especially new drug delivery application stability, solubility, biocompa...

Objective(s): Pseudomonas aeruginosais a Gram-negative and aerobic rod bacterium that displays mucoid and non-mucoid phenotype. Mucoid strains secrete alginate, which is the main agent of biofilms in chronic P. aeruginosa infections, show high resistance to antibiotics; consequently, the biological disruption of mucoid P. aeruginosa biofilms is an attractive area of study for researchers. Algin...

Abstract Wound management is a key feature in saving people’s lives, and regardless of the wound size, using appropriate dressing crucial. Alginate-based topical gels loaded with 2 mL essential oils (eucalyptus, lavender rosemary oil) combination 30 mg magnetite (Fe 3 O 4 ) nanoparticles 70 tranexamic acid were prepared. Carbopol was used as gelling agent surfactant to disperse EO. X-ray diffra...