نتایج جستجو برای: alcoholic hepatitis

تعداد نتایج: 158613  

2016
Hee Yeon Kim Chang Wook Kim Tae Yeob Kim Do Seon Song Dong Hyun Sinn Eileen L Yoon Young Kul Jung Ki Tae Suk Sang Soo Lee Chang Hyeong Lee Tae Hun Kim Jeong Han Kim Hyung Joon Yim Sung Eun Kim Soon Koo Baik Byung Seok Lee Jae Young Jang Young Seok Kim Sang Gyune Kim Jin Mo Yang Joo Hyun Sohn Heon Ju Lee Seung Ha Park Eun Hee Choi Dong Joon Kim

AIM To assess the performance of proposed scores specific for acute-on-chronic liver failure in predicting short-term mortality among patients with alcoholic hepatitis. METHODS We retrospectively collected data from 264 patients with clinically diagnosed alcoholic hepatitis from January to December 2013 at 21 academic hospitals in Korea. The performance for predicting short-term mortality was...

Journal: :Saudi medical journal 2014
Shi-Hua Zheng You-Ming Li Shao-Hua Chen Hai-Xiu Huang Guang-Jin Yuan

OBJECTIVE To investigate the clinical features of alcoholic liver disease (ALD) in hospitalized Chinese patients, and their differences compared with western countries. METHODS Four hundred and eight hospitalized patients with ALD at First Affiliated Hospital of Zhejiang University College of Medicine, Hangzhou, from January 2008 to December 2010 were studied retrospectively. Clinical data we...

Journal: :Transplantation 2001
C O Bellamy A M DiMartini K Ruppert A Jain F Dodson M Torbenson T E Starzl J J Fung A J Demetris

BACKGROUND Alcoholic liver disease has emerged as a leading indication for hepatic transplantation, although it is a controversial use of resources. We aimed to examine all aspects of liver transplantation associated with alcohol abuse. METHODS Retrospective cohort analysis of 123 alcoholic patients with a median of 7 years follow-up at one center. RESULTS In addition to alcohol, 43 (35%) p...

2011
D. S. Jayaprakash

Liver diseases are common disorders encountered in clinical practice. Investigations in Liver diseases are used to detect hepatic abnormality, to measure its severity, to define its structural effect on the liver to look for specific causes of Liver diseases to assess prognosis and to evaluate therapy. Aims and Objectives: To study and compare the altered serum levels of Alkaline phosphatase, B...

2017
Catherine E Kling James D Perkins Robert L Carithers Dennis M Donovan Lena Sibulesky

AIM To examine temporal changes in the indications for liver transplantation (LT) and characteristics of patients transplanted for alcoholic liver disease (ALD). METHODS We performed a retrospective cohort analysis of trends in the indication for LT using the United Network for Organ Sharing (UNOS) database between 2002 and 2015. Patients were grouped by etiology of the liver disease and char...

Journal: :Annals of hepatology 2014
Fátima Higuera-de la Tijera Alfredo I Servín-Caamaño Javier Cruz-Herrera Aurora E Serralde-Zúñiga Juan M Abdo-Francis Gabriela Gutiérrez-Reyes José L Pérez-Hernández

BACKGROUND & AIM Despite treatment with glucocorticoids, mortality remains high in patients with severe alcoholic hepatitis. Oxidative stress and depletion of mitochondrial glutathione are implicated factors in liver injury. The aim of this study was to evaluate the impact of the addition of metadoxine, a drug which possesses a multifactorial mechanism of action, including antioxidant propertie...

2012
Sadroddin Lahsaee Alireza Ghazizade Mahnaz Yazdanpanah Ahmad Enhesari Reza Malekzadeh

AIM The aim of this study was to review cases of non-alcoholic fatty liver disease cases and to determine the prevalence of non-alcoholic fatty liver disease as a cause of elevated alanine aminotransferase in healthy blood donors in the Permian area and also assess risk factors of NAFLD such as BMI and correlation with metabolic syndrome in these subjects. BACKGROUND Non-alcoholic fatty liver...

2017
Thomas Damgaard Sandahl Sidsel Hyldgaard Støy Tea Lund Laursen Sidsel Rødgaard-Hansen Holger Jon Møller Søren Møller Hendrik Vilstrup Henning Grønbæk

BACKGROUND AND AIMS Hepatic macrophages (Kupffer cells) are involved in the immunopathology of alcoholic liver disease (ALD). The mannose receptor (MR, CD206), expressed primarily by macrophages, mediates endocytosis, antigen presentation and T-cell activation. A soluble form, sMR, has recently been identified in humans. We aimed to study plasma sMR levels and its correlation with disease sever...

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