نتایج جستجو برای: alcoholic fatty liver disease nafld

تعداد نتایج: 1835563  

2014
Min Yang Sitang Gong Shui Qing Ye Beth Lyman Lanlan Geng Peiyu Chen Ding-You Li

With increasing prevalence of childhood obesity, non-alcoholic fatty liver disease (NAFLD) has emerged as the most common cause of liver disease among children and adolescents in industrialized countries. It is generally recognized that both genetic and environmental risk factors contribute to the pathogenesis of NAFLD. Recently, there has been a growing body of evidence to implicate altered gu...

Journal: :Open Access Macedonian Journal of Medical Sciences 2021

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is one of the common diseases worldwide that not associated with alcohol consumption; it a group disorders caused by fat accumulation in liver. AIM: The research aims to assess levels serum sialoprotein, sclerostin, and osteocalcin men NAFLD. METHODS: current study was conducted Basra city, Iraq 2020, which includes 400 NAFLD, age ranges bet...

Journal: :Metabolism: clinical and experimental 2015
Jia Liu Yuan Xu Yanjin Hu Guang Wang

Non-alcoholic fatty liver disease (NAFLD) includes a cluster of liver disorders ranging from simple fatty liver to non-alcoholic steatohepatitis (NASH) and cirrhosis. Due to its liver and vascular complications, NAFLD has become a public health problem with high morbidity and mortality. The pathogenesis of NAFLD is considered a "multi-hit hypothesis" that involves lipotoxicity, oxidative stress...

2008
John Vierling

78 New Techniques Redefine Assessment of Liver Disease Research introduces unique methods for evaluating patients with non-alcoholic fatty liver disease (NAFLD). NAFLD is the most common liver disease in the world and the development of novel procedures for definitively diagnosing the disease and assessing its prognosis is extremely important for tailoring effective treatments. “Defeating the m...

Journal: :The EMBO journal 2016
Bárbara González-Terán Nuria Matesanz Ivana Nikolic María Angeles Verdugo Vinatha Sreeramkumar Lourdes Hernández-Cosido Alfonso Mora Georgiana Crainiciuc María Laura Sáiz Edgar Bernardo Luis Leiva-Vega Elena Rodríguez Victor Bondía Jorge L Torres Sonia Perez-Sieira Luis Ortega Ana Cuenda Francisco Sanchez-Madrid Rubén Nogueiras Andrés Hidalgo Miguel Marcos Guadalupe Sabio

Non-alcoholic fatty liver disease (NAFLD) is a major health problem and the main cause of liver disease in Western countries. Although NAFLD is strongly associated with obesity and insulin resistance, its pathogenesis remains poorly understood. The disease begins with an excessive accumulation of triglycerides in the liver, which stimulates an inflammatory response. Alternative p38 mitogen-acti...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه پیام نور - دانشگاه پیام نور استان تهران - دانشکده علوم پایه 1389

سابقه و هدف: بیماری کبد چرب غیرالکلی شایعترین بیماری مزمن کبدی در جهان است. بسیاری از مطالعات انجام شده بر روی افراد مبتلا به این بیماری چاقی، دیابت و دیس لیپیدمی را از عوامل خطر این بیماری معرفی کرده اند. در عین حال برخی از مطالعات بروز این بیماری را در افراد غیرچاق غیردیابتی گزارش نموده اند. هدف این مطالعه بررسی و شناخت عوامل خطر بروز بیماری کبد چرب غیر الکلی (nafld- non alcoholic fatty liver...

2016
Bárbara González-Terán Nuria Matesanz Ivana Nikolic María Angeles Verdugo Vinatha Sreeramkumar Lourdes Hernández-Cosido Alfonso Mora Georgiana Crainiciuc María Laura Sáiz Edgar Bernardo Luis Leiva-Vega Elena Rodríguez Victor Bondía Jorge L Torres Sonia Perez-Sieira Luis Ortega Ana Cuenda Francisco Sanchez-Madrid Rubén Nogueiras Andrés Hidalgo Miguel Marcos Guadalupe Sabio

Non-alcoholic fatty liver disease (NAFLD) is a major health problem and the main cause of liver disease in Western countries. Although NAFLD is strongly associated with obesity and insulin resistance, its pathogenesis remains poorly understood. The disease begins with an excessive accumulation of triglycerides in the liver, which stimulates an inflammatory response. Alternative p38mitogen-activ...

آبانگاه, قباد, اسداللهی, خیرالله, سایه میری, کورش, مرادی کهنکی, زینب,

Background: Considering the high incidence and prevalence of nonalcoholic fatty liver disease (NAFLD) in the Iranian society and the limited number of studies to investigate its associated risk factors, the current study was designed to identify any relevant risk factor of this disease. Methods: The present case-control study was performed among 150 nonalcoholic fatty liver disease patien...

2014
Robert N. Schuck Weibin Zha Matthew L. Edin Artiom Gruzdev Kimberly C. Vendrov Tricia M. Miller Zhenghong Xu Fred B. Lih Laura M. DeGraff Kenneth B. Tomer H. Michael Jones Liza Makowski Leaf Huang Samuel M. Poloyac Darryl C. Zeldin Craig R. Lee Hervé Guillou

Fatty liver disease is an emerging public health problem without effective therapies, and chronic hepatic inflammation is a key pathologic mediator in its progression. Cytochrome P450 (CYP) epoxygenases metabolize arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs), which have potent anti-inflammatory effects. Although promoting the effects of EETs elicits anti-inflammatory...

2017
Abbas Tavakolian Arjmand

A growing number of published papers consider the nonalcoholic fatty liver disease (NAFLD) and cryptogenic cirrhosis as the immediate offspring of Type 2 diabetes mellitus (T2DM). NAFLD is the most common liver disorder in developed countries, where up to 80% of obese people have the disease. Cirrhosis is defined as the advanced stages of hepatic fibrosis with characteristic distortion of hepat...

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