Abstract Background Delirium is an acute onset of clinical serious conditions associated with poor outcomes, seen in older patients Emergency Department (ED). Despite its seriousness, delirium can be missed by 57-83% and 25% unrecognised discharged from ED. The audit aim to improve screening for people ED using the 4AT assessment tool. Methods Criteria included over 75 under complaints new conf...

OBJECTIVES This work consists in a study of the links between alcohol, a psychoactive substance and different related epileptic manifestations in order to clarify predominant factors both on conceptual, clinical and therapeutic levels. BACKGROUND If alcohol is a frequent risk factor for seizures, its scientific evidence is less clear and ad hoc literature is rich in controversies and not firm...

Background: Delirium is a distressing neuropsychiatric disorder affecting patients in palliative care. Although many delirium screening tools exist, their utility, and validation within care settings has not undergone systematic review. Aim: To systematically review studies that validate conducted settings. Design: Systematic with narrative synthesis (PROSPERO ID: CRD42019125481). A risk of bia...

BACKGROUND Alcohol is the leading psychoactive substance consumed in France, with about 15 million regular consumers. The National institute on Alcohol Abuse and Alcoholism (NIAAA) considers alcohol abuse to be more than 14 units of alcohol a week for men and 7 units for women. The specific complication of alcoholism is the alcohol withdrawal syndrome. Its incidence reaches up to 30 % and its m...

Introduction We sought to detect a relationship between midazolam concentration and development of new delirium in critically ill children who were on continuous administration. Methods Delirium was detected using the Sophia Observation withdrawal Symptoms - Paediatric (SOS-PD) score 104 left-over samples available measure concentrations. Results Twenty-five percent included patients developed ...

AIMS Aggressive and criminal traits have a complex genetic background which interacts with environmental factors. Alcohol intoxication has been related to lower thresholds of aggressive behaviors. In this association study of two independent samples, a number of candidate gene variants (5HT2A T102C, 5-HTTLPR, DRD Ins-141Del, DAT1 VNTR) were related to violent criminal behavior and alcohol-relat...

The past 100 years witnessed the formation of a disease concept of alcoholism and a rapid increase in the knowledge of its aetiopathology and treatment options. In the first half of the century, public sanctions aimed at the abolition of alcoholism. In the United States, alcohol prohibition was revoked in the economic turmoil of the Great Depression. In Germany, proposed medical procedures to r...