Response of a transversely isotropic 3-D half-space subjected to a surface time-harmonic excitation is presented in analytical form. The derivation of the fundamental solutions expressed in terms of displacements is based on the prefect series of displacement potential functions that have been obtained in the companion paper by the authors. First the governing equations are uncoupled in the cyl...

Chronic endoplasmic reticulum (ER) stress culminating in proteotoxicity contributes to the development of insulin resistance and progression to type 2 diabetes mellitus. Pharmacologic interventions targeting several different nuclear receptors have emerged as potential treatments for insulin resistance. The mechanistic basis for these antidiabetic effects has primarily been attributed to multip...

Although studies provide insights into the neurobiology of stress and depression, the exact molecular mechanisms underlying their pathologies remain largely unknown. Long non-coding RNA (lncRNA) has been implicated in brain functions and behavior. A potential link between lncRNA and psychiatric disorders has been proposed. However, it remains undetermined whether IncRNA regulation, in the brain...

The proper functioning of the endoplasmic reticulum (ER) is crucial for multiple cellular activities and survival. Disturbances in the normal ER functions lead to the accumulation and aggregation of unfolded proteins, which initiates an adaptive response, the unfolded protein response (UPR), in order to regain normal ER functions. Failure to activate the adaptive response initiates the process ...

Schizotypy, defined in terms of commonly occurring personality traits related to the schizophrenia spectrum, has been an important construct for understanding the neurodevelopment and stress-diathesis of schizophrenia. However, as schizotypy nears its sixth decade of application, it is important to acknowledge its impressively rich literature accumulating outside of schizophrenia research. In t...

Phosphoinositides are key lipids in eukaryotes, regulating organelles' identity and function. Their synthesis turnover require specific phosphorylation/dephosphorylation events that ensured by dedicated lipid kinases phosphatases, which modulate the structure of inositol ring adding or removing phosphates on positions 3, 4 5. Beside their implication intracellular signalization cytoskeleton dyn...