OBJECTIVE To evaluate the safety and effectiveness of high-frequency oscillatory ventilation using a protocol designed to recruit and maintain optimal lung volume in patients with severe adult respiratory distress syndrome (ARDS). SETTING Surgical and medical intensive care units in a tertiary care, military teaching hospital. DESIGN A prospective, clinical study. PATIENTS Seventeen patie...

BACKGROUND In patients with acute respiratory distress syndrome, whether inverse ratio ventilation differs from high positive end-expiratory pressure (PEEP) for gas exchange under a similar mean airway pressure has not been adequately examined. The authors used arterial oxygenation, gastric intramucosal partial pressure of carbon dioxide (PiCO(2)), and pH (pHi) to assess whether pressure-contro...

INTRODUCTION — Conventional mechanical ventilation refers to the delivery of full or partial ventilatory support by a volume-cycled mechanical ventilator or by pressure support. It also can include the maintenance of positive airway pressure at the end of exhalation, ie, positive end-expiratory pressure (PEEP) [1]. (See "Physiologic and pathophysiologic consequences of positive pressure ventila...

The efficacy of two triggering systems was compared during neonatal patient triggered ventilation: the Graseby MR10 respiration monitor and airway pressure changes. Ten preterm infants were studied, median gestational age 33 weeks (range 28-35). Patient triggered ventilation was administered via the SLE ventilator at a series of inflation times (0.24, 0.3, and 0.4 seconds). Comparison was made ...

Background Noninvasive ventilation (continuous positive airway pressure [CPAP] or noninvasive intermittent positive-pressure ventilation [NIPPV]) appears to be of benefit in the immediate treatment of patients with acute cardiogenic pulmonary edema and may reduce mortality. We conducted a study to determine whether noninvasive ventilation reduces mortality and whether there are important differ...

Background: Previous studies have shown that progesterone increases the ventilatory performance in healthy individuals and in patients with chronic obstructive pulmonary disorders. The study was designed to investigate the effect of a single intramuscular administration of progesterone on ventilatory performance in adult trauma patients during partial support mechanical ventilation. Methods: Fo...

expiratory pressure; Phihigh airway pressure level with BiPAP; Plolow airway pressure level with BiPAP; PSVpressure support ventilation; PVRlpulmonary vascular resistance index; RVEDVright ventricular enddiastolic volume; RVEFright ventricular ejection fraction; RVESVright ventricular end-systolic volume; RVPSPright ventricular peak systolic pressure; RVSV right ventricular stroke volume; RVSWI...

STUDY OBJECTIVE The validation of electrical impedance tomography (EIT) for measuring regional ventilation distribution by comparing it with single photon emission CT (SPECT) scanning. DESIGN Randomized, prospective animal study. SETTINGS Animal laboratories and nuclear medicine laboratories at a university hospital. PARTICIPANTS Twelve anesthetized and mechanically ventilated pigs. INT...