background: cuffed pharyngeal tube is a device designed for ventilation of anesthetized patients. cpt has advantages over face mask including: maintaining of face mask can be difficult and boring after several minutes and mobility of the practitioner is reduced due to involvement of hands. mask pressure can cause soft tissue and nerve damage around the nose. anesthetic gas leakage from the mask...

RATIONALE Recent literature suggests that adult bone marrow-derived cells can localize to lung and acquire immunophenotypic characteristics of lung epithelial cells. We speculated this might be a potential therapeutic approach for correcting defective lung epithelium in cystic fibrosis. OBJECTIVE To determine whether adult bone marrow-derived cells containing normal cystic fibrosis transmembr...

Increased or altered collagen deposition in the airway wall is one of the characteristics of airway remodelling in asthma. The mechanisms underlying this increase, and its functional consequences remain to be established further. Representative in vivo animal models might be useful in this respect. In the present study, collagen deposition after prolonged allergen exposure was characterised in ...

In a previous case report, we determined for the first time that uvulopalatopharyngoplasty (UPPP) does not change the volume of the upper airway but causes morphological changes in the entire upper airway. The objective of this study is to elucidate the mechanisms underlying the improvement in obstructive sleep apnea syndrome (OSAS) by UPPP. We present an additional case involving a patient wit...

cystic fibrosis (cf) is an inherited disease that primarily affects the lungs and the digestive system, however, it also affects a number of other organs and systems. more than 90% of mortality of  cf patients is due to lung complications.  healthy lungs are important for a long life for people with cf, we will discuss two important topics for maintaining respiratory health. chronic use of drug...

BACKGROUND Portable oxygen concentrators (POCs) typically include pulse flow (PF) modes to conserve oxygen. The primary aims of this study were to develop a predictive in vitro model for inhaled oxygen delivery using a set of realistic airway replicas, and to compare PF for a commercial POC with steady flow (SF) from a compressed oxygen cylinder. METHODS Experiments were carried out using a s...

BACKGROUND Asthma is characterized by chronic airway inflammation, airway hyperresponsiveness (AHR), and airway remodeling. While exposure of house dust mites (HDM) is a common cause of asthma, the pathogenesis of the HDM-induced asthma is not fully understood. Bronchopulmonary C-fibers (PCFs) contribute to the neurogenic inflammation, viral infection induced-persistent AHR, and ovalbumin induc...

The pathophysiological characteristics of bronchial asthma consist of chronic inflammation of airways, airway hyperresponsiveness, and bronchoconstriction. Studies have shown that T helper type 2 (Th2) cytokines produced by both T cells and mast cells in the airway contribute substantially to the initiation of inflammation in both experimental and human bronchial asthma. GATA-3 is a transcripti...

The role of an enlarged goiter for the airway management in patient populations undergoing thyroidectomy has rarely been studied. The main objective of this study was to assess the incidence and predictive factors of difficult airway in patients undergoing thyroidectomy. The study was designed as a prospective observation carried out to determine the incidence of difficult mask ventilation, dif...

The rationale for airway clearance therapy and basic principles of its application are identical for children and adults, but there are important differences in physiology (regarding airway mucus characteristics and airway mechanics) and pathological processes in children, as well as other considerations unique to the pediatric population. The major obstacle in reviewing the evidence for effica...