Acute interstitial nephritis (AIN) is a common cause of acute kidney injury and has been associated with a variety of medications. This is the case of 30-year-old man with Hodgkin's lymphoma who on routine labs before chemotherapy was found to have acute nonoliguric renal failure. A kidney biopsy was performed and confirmed the diagnosis of acute interstitial nephritis. The patient had taken se...

BACKGROUND Studies of human immunodeficiency virus (HIV)-positive men have demonstrated high rates of anal intraepithelial neoplasia (AIN), a precursor to anal carcinoma, mostly in white homosexual men and men not receiving effective antiretroviral therapy (ART). METHODS Ninety-two participants--53% Latino, 36% African American, and 40% without a history of receptive anal intercourse (RAI)--w...

Low vitamin E and selenium (Ve/Se) nutritional status is known to be associated with increased risk of esophageal squamous cell carcinoma (ESCC). A previous human intervention trial demonstrated that Ve/Se supplementation decreased the occurrence of esophageal cancer death among younger participants but not among older ones. In this study, we intended to mimic this human nutritional status to d...

Cocaine is abused worldwide as a recreational drug. It is a potent activator of the sympathetic nervous system leading to intense vasoconstriction, endothelial dysfunction, oxidative stress, platelet activation and decrease in prostaglandins E2 and prostacyclin. Cocaine can lead to widespread systemic adverse effects such as stroke, myocardial infarction, arterial dissection, vascular thrombosi...

This study investigated the effect of tucum-do-cerrado consumption in the oxidative status of iron-supplemented rats. Four groups of rats were treated: Control (AIN-93G), Tuc (AIN-93G added of tucum-do-cerrado), Fe (AIN-93G iron-enriched), or TucFe (AIN-93G with tucum-do-cerrado and iron-enriched) diet, for 30 days. Iron-enriched diet increased serum, liver, spleen, and intestine iron levels; t...

Vibrio fischeri possesses two acyl-homoserine lactone quorum-sensing systems, ain and lux, both of which are involved in the regulation of luminescence gene expression and are required for persistent colonization of the squid host, Euprymna scolopes. We have previously demonstrated that the ain system induces luminescence at cell densities that precede lux system activation. Our data suggested ...

We studied DNA methylation patterns of human papillomavirus (HPV) and tumor suppressor gene EPB41L3 in 148 anal and perianal biopsies to determine whether high levels of methylation would be associated with anal intraepithelial neoplasia (AIN). The most prevalent HPV type was HPV16, detected in 54% of the 30 benign biopsies, 33% of the 43 low-grade AIN (lgAIN), 82% of the 59 high grade AIN (hgA...

In this paper, we propose an integrated methodology for specifying AIN and switch-based features and analyzing their interactions in the AIN 0.1 framework. The specification of each individual feature is tied to the AIN call model and requires only minimum amount of information in terms of control and data for interaction analysis. Once a feature is specified, its specification is then validate...

AMA Fitting G, Loichle A, Kakarlapudi R, Puthiyathu M. Hyperactive delirium as a complication of nicotine withdrawal: case report. Alcoholism and Drug Addiction/Alkoholizm i Narkomania. 2023;36(1):53-58. doi:10.5114/ain.2023.129508. APA Fitting, G., Loichle, A., Kakarlapudi, R., & Puthiyathu, (2023). Narkomania, 36(1), 53-58. https://doi.org/10.5114/ain.2023.129508 Chicago Grace, Autumn Raju Ma...

AMA Moskalewicz J, Garretsen H, Room R. A half-century of the Kettil Bruun Society: a history against backdrop global developments. Alcoholism and Drug Addiction/Alkoholizm i Narkomania. 2022;35(4):293-306. doi:10.5114/ain.2022.126480. APA Moskalewicz, J., Garretsen, H., & Room, (2022). Narkomania, 35(4), 293-306. https://doi.org/10.5114/ain.2022.126480 Chicago Jacek, Henk Robin Room. 2022. "A ...