The evidence indicating that platelets may play a role in the occurrence of certain thromboembolic phenomena has stimulated a search for inhibitors of platelet function. This report presents data to indicate that nitrofurantoin is a potent inhibitor of primary ADP-induced platelet aggregation. The addition of 10 muM nitrofurantoin to citrated platelet-rich plasma obtained from 12 normal subject...

Intrinsically Disordered Proteins (IDPs) are characterized by the lack of well-defined 3-D structure and show high conformational plasticity. For this reason, they are a strong challenge for the traditional characterization of structure, supramolecular assembly and biorecognition phenomena. We show here how the fine tuning of protein orientation on a surface turns useful in the reliable testing...

In nature, fractal structures emerge in a wide variety of systems as a local optimization of entropic and energetic distributions. The fractality of these systems determines many of their physical, chemical and/or biological properties. Thus, to comprehend the mechanisms that originate and control the fractality is highly relevant in many areas of science and technology. In studying clusters gr...

To reduce the data volume, various algorithms have been proposed for data compression and data aggregation. In object tracking applications, natural phenomena show that many creatures form large social groups and move in regular patterns. However, the previous works do not address application level semantics, such as the group relationships and movement patterns, in the location data. In this p...

We study in detail the application of renormalisation theory to models of cluster aggregation and fragmentation of relevance to nucleation and growth processes. We investigate the Becker-Döring equations, originally formulated to describe and analyse non-equilibrium phase transitions, and more recently generalised to describe a wide range of physicochemical problems. In the present paper we ana...

Abstract. Size-structured population models provide a popular means to mathematically describe phenomena such as bacterial aggregation, schooling fish, and planetesimal evolution. For parameter estimation, generalized sensitivity functions (GSFs) provide a tool that quantifies the impact of data from specific regions of the experimental domain. These functions help identify the most relevant da...

Demand response resources (DRRs) are usually aggregated in order to participate in wholesale electricity markets (e.g., capacity, energy, and ancillary service markets). In such DRR aggregation systems, uncertainty arising from, e.g., random failures, is unavoidable; this paper focuses on assessing the impact of such uncertain phenomena on the reliability of DRR aggregation systems. To this end...

Diffusion-limited aggregation (DLA) is a useful model for studying such common physical phenomena as dust clustering, unstable fluid flowJ chemical species precipitation, and crystal growth. Simulating the DLA processes using electrostatic analogy is very computation-intensive. Elimination of closed loops in DLA images can significantly reduce the dimensionality of the problem and minimize the ...

This article shows that the introduction of the Surface Complexation model into the »family« of theories that comprise the Theory of Colloid Stability makes that theory »absolute«. This means that one characterizes the electrical interfacial layer, e.g. by adsorption measurements, and calculates the equilibrium parameters, such as the equilibrium constants of protonation and deprotonation of am...

Under starvation conditions, a population of myxobacteria aggregates to build a fruiting body whose shape is species-specific and within which the cells sporulate. Early in this process, cells often pass through a "ripple phase" characterized by traveling linear, concentric, and spiral waves. These waves are different from the waves observed during slime mold aggregation that depend on diffusib...