This paper offers a comprehensive study of information aggregation in intelligent systems prompted by common engineering interest. After a motivating introduction we consider aggregation functions and their fundamental properties as a basis for further development. Four main classes of aggregation functions are identified, and important subclasses are described and characterized as prototypes. ...

Protein aggregation and precipitation is associated with many debilitating diseases including Alzheimer's, Parkinson's, and light-chain amyloidosis. β-Casein, a member of the casein family, has been demonstrated to exhibit chaperone-like activity to protect protein form aggregation. Hofmeister salts (lyotropice series) are a class of ions which have an effect on the solubility and also the stab...

Aggregation operators (AOs) have been studied by many schol- ars. As many AOs are proposed, there is still lacking approach to classify the categories of AO, and to select the appropriate AO within the AO candidates. In this research, each AO can be regarded as a cognitive style or individual dierence. A Cognitive Style and Aggregation Operator (CSAO) model is pro- posed to analyze the mapping ...

Epidemiologic studies show that the cardiovascular diseases are associated with multiple factors such as raised serum total cholesterol, increased LDL, increased platelet aggregation, hypertension and smoking. In-vitro studies have confirmed the ability of some plants of Allium species to reduce these parameters. Therefore, we evaluated anti-platelet aggregation effect of some Allium species (A...

BACKGROUND We observed that the prodrug clopidogrel was less effective in inhibiting platelet aggregation with coadministration of atorvastatin during point-of-care platelet function testing. Because atorvastatin is metabolized by cytochrome P450 (CYP) 3A4, we hypothesized that clopidogrel might be activated by CYP3A4. METHODS AND RESULTS Platelet aggregation was measured in 44 patients under...

In this paper, we focus on maximizing the network lifetime of wireless sensor networks using both maximum lifetime routing algorithm and smoothing function. An optimal routing and data aggregation scheme for wireless sensor networks is proposed. The objective is to maximize the network lifetime by jointly optimizing data aggregation and routing by adopting a model to integrate data aggregation ...

The aggregation promoter heparin is commonly used to study the aggregation kinetics and biophysical properties of protein amyloids. However, the underlying mechanism for amyloid promotion by heparin remains poorly understood. In the case of the neuropeptide β-endorphin that can reversibly adopt a functional amyloid form in nature, aggregation in the presence of heparin leads to a loss of functi...

The aggregation promoter heparin is commonly used to study the aggregation kinetics and biophysical properties of protein amyloids. However, the underlying mechanism for amyloid promotion by heparin remains poorly understood. In the case of the neuropeptide b-endorphin that can reversibly adopt a functional amyloid form in nature, aggregation in the presence of heparin leads to a loss of functi...

BACKGROUND AND PURPOSE Nimodipine, a calcium antagonist, has been reported to have beneficial effects in acute ischemic infarction. Some calcium channel antagonists have antiplatelet effects. We investigated the effect of oral nimodipine on platelet function in healthy volunteers. METHODS Twelve healthy volunteers (6 men and 6 women, mean age 32.9 +/- 5.6 years) took 30 mg nimodipine every 6 ...