introduction: both midazolam and promethazine are recommended to be used as sedatives in many studies but each have some side effects that limits their use. combination therapy as an alternative method, may decreases these limitations. therefore, this study aimed to compare midazolam with midazolam-promethazine regarding induction, maintenance, and recovery characteristics following pediatric p...

background: staphylococcus aureus is a major human pathogen. due to high prevalence of s. aureus infections and increasing resistance to antibiotics, physicians have been facing problems in choosing the appropriate empirical antibiotic therapy for such infections. objectives: the aim of this study was to determine the pattern of antibiotic resistance in s. aureus clinical isolates of mashhad qu...

case report: besides the interaction with other drugs (mainly warfarin and amiodarone). orlistat´s mainly side effects are gastrointestinal disorders such as the existence of oily spotting from the rectum, abdominal pain or discomfort, fecal urgency. there are also side effects at other levels, like flu symptoms, hypoglycemia, heathache or upper respiratory infections. there are other side effe...

background and purpose: today, one of the major health problems worldwide is cancer. several factors are involved in cancer incidence; however, the role of environmental factors is more prominent. modifying these factors and changing them into proper behavior can have a fundamental role in preventing cancer. accordingly, this study was conducted to evaluate the exposure to carcinogenic agents i...

conclusions we discovered a consistent reduction of serum ace levels by two oral antiviral monotherapies, entecavir and telbivudine. serum ace levels were negatively correlated with egfrs in telbivudine treated patients. objectives we aimed to investigate changes in serum protein abundances associated with renal function in response to antiviral treatments. materials and methods primarily, a tr...

background: androgenic-anabolic steroids (aas) are abused by a growing number of bodybuilders. this descriptive cross-sectional study was conducted to determine prevalence and patterns of aas use by bodybuilders in hamadan, western iran. methods: in this cross-sectional study, participants were recruited from five gym clubs in two area of hamadan (a total of 10 clubs). twenty-five bodybuilders ...

general population surveys often report that only a small proportion of individuals with common mental disorders seek mental health treatment, suggesting a high level of unmet need for mental health care in the community. in recent years, however, the number of adults in industrialized countries who are treated with antidepressant medications has dramatically increased. this paper reviews the p...

background: thalassemia is a series of hemoglobinopathies in which the production of perfect hemoglobin is completely or partially suppressed. using injectable iron chelators have been dominating treatment for the iron overload caused by recurrent blood transfusions in thalassemic patients, however, a new oral iron chelating drug (exjade) have been recently introduced and might be cost effectiv...

background: emergence of antimicrobial resistance toward a number of conventional antibiotics has triggered the search for antimicrobial agents from a variety of sources including the marine environment. objectives: the aim of this study was to evaluate the antimicrobial potential of holothuria leucospilota from qeshm and kharg islands against some selected bacteria and fungi. materials and met...

conclusions if medical treatment gets started early in the course of empyema, prognosis would be excellent. besides, there was no significant difference in short- and long-term outcomes between medical or surgical interventions. objectives the aim of this study was to compare the duration of admission, duration of intravenous antibiotic therapy, time to response to treatment, and outcomes of me...