Aflatoxin levels in animal feed should be observed from the farm to table ensure safety of animals and humans. The contamination cereals other agricultural supplies used production could happen pre-harvest phase or post-harvest phase. study sought determine broiler selected farms Nairobi City County. A total 42 samples were collected. Samples analyzed using LCMS/MS technique. Results show that ...

background: aflatoxins are the most common mycotoxins that contaminate crops. they are produced by fungi such as aspergillus flavus and aspergillus parasiticus . wheat ( tricitumaestivum ) is one of the most important staple foods used in iran, and the environmental conditions in the north of iran are favorable to fungal growth. this study was designed in order to determine the aflatoxin concen...

AbstractPregnant women and their developing fetuses are vulnerable to multiple environmental insults, including exposure to aflatoxin, a mycotoxin that may contaminate as much as 25% of the world food supply. We reviewed and integrated findings from studies of aflatoxin exposure during pregnancy and evaluated potential links to adverse pregnancy outcomes. We identified 27 studies (10 human cros...

We have examined the time course and patterns of covalent aflatoxin B^DNA adducts produced within the ribosomal RNA gene sequences isolated from the liver nuclear DNA of aflatoxin Bi-treated animals. Liver nuclear DNA was initially enriched in ribosomal DNA by cesium salt density centrifugaron, and incu bated under alkaline conditions to stabilize bound aflatoxin ST ONA moieties. Alkali-treated...

Administration of[3H]aflatoxin B2 (2,3-dihydroaflatoxin B1)(AFB2) to male rats resulted in levels of hepatic DNA- and ribosomal(r)RNA-aflatoxin adducts that were about 1% of those for rats given [3H]aflatoxin B1(AFB1). The levels of hepatic protein-aflatoxin adducts were 35 to 70% as great for AFB2-treated as compared to AFB1-treated rats...

Tolnaftate [2-napthyl-N-methyl-N-(m-tolyl)thionocarbamate], an antifungal drug, is widely used to control superficial fungal infections in humans and other animals. In this study the effect of tolnaftate on aflatoxin biosynthesis by Aspergillus parasiticus NRRL 3240 was investigated. Tolnaftate changed the morphology of A. parasiticus to yeastlike forms and inhibited aflatoxin formation. The fo...

Mycotoxins which mainly consist of Aflatoxin (AF), Zearalenone (ZEN) and Deoxynivalenol (DON) are commonly found in many food commodities. Although each component has been shown to cause liver toxicity and oxidative stress in several species, there is no evidence regarding the effect of naturally contained multiple mycotoxins on tissue toxicity and oxidative stress in vivo. In the present study...

During 2011~2013, a total of 729 samples for 19 types of medicinal plant were collected from Seoulyekryungsi in Seoul, Korea, and investigated for the presence of aflatoxins. The samples were analyzed using immunoaffinity column cleanup and high-performance liquid chromatography coupled to a fluorescence detector after post-column derivatization. Aflatoxins were found in 124 out of the 729 anal...

Occurrence of aflatoxins in crops has vast impacts on human health. Therefore, the study of aflatoxin biosynthesis has become important. Previous studies have shown that the aflatoxin biosynthesis gene cluster and several genes, enzymes, and regulatory elements are involved in aflatoxin biosynthesis; however, the intricate metabolic regulatory networks of aflatoxin synthesis remain unclear. Rap...

West African Aspergillus flavus S isolates differed from North American isolates. Both produced aflatoxin B1. However, 40 and 100% of West African isolates also produced aflatoxin G1 in NH4 medium and urea medium, respectively. No North American S strain isolate produced aflatoxin G1. This geographical and physiological divergence may influence aflatoxin management.