Background: Due to their inherent characteristics, neonates hospitalized in the neonatal intensive care units are more often exposed to medication errors and its adverse effects. The aim of this study is to determine the reasons for failure to report Adverse Drug Reaction (ADR) experienced by nurses employed at these units in educational and treatment centers affiliated to the Iran University o...

Background Infliximab and adalimumab are monoclonal antibodies to tumor necrosis factor alpha (TNF-á) used in the treatment of various inflammatory disorders. Infliximab, a chimeric monoclonal antibody, is postulated to be more immunogenic as it is not entirely humanized. Despite reports of adalimumab treatment in patients after an adverse reaction to infliximab, there is a paucity of literatur...

Background and Objectives: Pharmacovigilance is central to the control of the menace of adverse drugs reactions. Despite the fact that development of policy and practice framework to improve patients’ safety partly rely on availability of authentic data on pharmacovigilance activities, knowledge about pharmacovigilance activities among healthcare professionals in Nigeria is limited. To help fil...

1. Attitudes of doctors to the Committee on Safety of Medicines' (CSM) adverse drug reaction (ADR) reporting scheme were investigated in order to assess their understanding of the purposes of the scheme and to identify reasons for failing to report suspected adverse drug reactions. 2. A postal questionnaire and letter of invitation were sent to 500 doctors who were randomly selected from the 19...

PURPOSE The improvement and linkage of two Department of Veterans Affairs (VA) databases for monitoring adverse drug reactions (ADRs) are described, with a discussion of the potential implications for improved medication safety within the VA health care system. SUMMARY Before 2007, VA had limited capability to track and evaluate ADRs across its nationwide network of health care facilities. Si...

The Veterinary Pharmacovigilance and Medicines Information Centre is responsible for the monitoring of veterinary adverse drug reactions in South Africa. An overview of reports of suspected adverse drug reactions received by the centre during the period March 2003 to February 2004 is given. A total of 20 reports was received. This had declined from the previous year. The general apathy with reg...

OBJECTIVE To evaluate the results of an intervention to improve the number and relevance of reports of adverse drug reactions. METHODS A cluster-randomized controlled trial was conducted with pharmacists working in Northern Portugal, in 2007. After randomization, 364 individuals were placed into the intervention group (261 in telephone interviews and 103 in workshops), while the control group...