INTRODUCTION Human immunodefiecency virus infected patients did not adhere correctly to their Antiretroviral Therapy because of the drugs adverse effects. Thus, continuous evaluation of the adverse effect of Antiretroviral Therapy will help to make more effective treatment. The aim of this study was to assess the prevalence of Adverse Drug Reaction and associated factors on Antiretroviral Thera...

results: a total number of 117 patients were evaluated for adverse drug reactions, among them, 97 (82.9%) were considered to have immunological drug reactions. the most common symptoms of allergic drug reactions were morbilliform eruptions, serum sickness, dress (drug rash with eosinophilia and systemic symptoms), and toxic epidermal necrolysis. in 62 patients, anticonvulsant drugs had the prom...

Diphenhydramine, as an antihistamine drug is widely used for the treatment of allergies. However, being classified as an over the counter medication and the general belief on the low adverse effect profile of this drug has made it widely accessible to the families. Recent reports of diphenhydramine intoxication and mortality, noticeably in children and infants have raised some serious concerns....

drug prescription errors are a common cause of adverse incidents and may lead to adverse outcomes, sometimes in subtle ways, being compounded by circumstances or further errors. therefore, it is important that veterinarians issue the correct drug at the correct dose. using two or more prescribed drugs may lead to drug interactions. some drug interactions are very harmful and may have potential ...

OBJECTIVE Adverse drug events (ADEs) are common and account for 770 000 injuries and deaths each year and drug interactions account for as much as 30% of these ADEs. Spontaneous reporting systems routinely collect ADEs from patients on complex combinations of medications and provide an opportunity to discover unexpected drug interactions. Unfortunately, current algorithms for such "signal detec...

introduction: previous studies have raised the probably of cardiac manifestation in tramadol poisoning. however, conclusive information on electrocardiographic (ecg) abnormalities of tramadol overdose remains to be explained. therefore, the present study aimed to evaluate the epidemiology of ecg abnormalities in tramadol poisoned patients. methods: in a prospective cross-sectional study, all pa...

objectives: graft versus host disease (gvhd) is a life threatening reaction in the stem cell transplantation process. nowadays cyclosporine is the most commonly utilized agent for gvhd prophylaxis and it has a major role in successful transplantation. cyclosporine has been applied for many years in this field but it could be stated that currently no general consensus is available for its optima...