The rfaD gene product, ADP-L-glycero-D-mannoheptose-6-epimerase, is necessary for the conversion of ADP-D-glycero-D-mannoheptose to ADP-L-glycero-Dmannoheptose. The nucleotide ADP-D-glycero-D-mannoheptose accumulates in rfaD mutant strains. Two chimeric colicin E l plasmids carrying the coding sequence of the rfaD+ locus have been selected and shown to complement the rfaD phenotype. These clone...

An ADP selective fluorescent probe working in aqueous medium was identified and the change in fluorescence as a function of ADP concentration was standardized. Using this probe, all the steps of glycolysis coupled with ATP/ADP inter-conversion and oxidative breakdown of pyruvate in the mitochondria were monitored and the consumption/production of ATP/ADP at each step was quantified. The quantit...

Some hyperthermophilic archaea use a modified glycolytic pathway that employs an ADP-dependent glucokinase (ADP-GK) and an ADP-dependent phosphofructokinase (ADP-PFK) or, in the case of Methanococcus jannaschii, a bifunctional ADP-dependent glucophosphofructokinase (ADP-GK/PFK). The crystal structures of three ADP-GKs have been determined. However, there is no structural information available f...

Eco-driving control generates significant energy-saving potential in car-following scenarios. However, the influence of preceding vehicle may impose unnecessary velocity waves and deteriorate fuel economy. In this research, a learning-based method is exploited to achieve satisfied economy for connected plug-in hybrid electric vehicles (PHEVs) with advantage vehicle-to-vehicle communication syst...

In this paper, we present a new adaptive dynamic programming (ADP) scheme to solve the optimal control problem of multi-player systems with unknown dynamics from perspective nonzero-sum (NZS) games. presented scheme, iterative equation is given. On basis given equation, policy and corresponding value function for each player can be learned by using state input data, which does not need identify...

Much discussion has concerned the central role of ADP in platelet aggregation. We now describe a patient (M.L.) with an inherited bleeding disorder whose specific feature is that ADP induces a limited and rapidly reversible platelet aggregation even at high doses. Platelet shape change and other hemostatic parameters were unmodified. A receptor defect was indicated, for, while epinephrine norma...

Oxidation of a-ketoisocaproate (KIC, 4-methyl-2-oxopentanoate) by coupled liver mitochondria was inhibited 60-70% by 1 m~ AMP, ADP, or its analogue, adenosine-5’-0-(2-thodiphosphate); inhibition was blocked by atractyloside. AMP inhibition was mediated by ADP generated via adenylate kinase. ADP inhibition was timeand temperature-dependent and required mitochondrial integrity. Oxidation of a-ket...