The adhesions and cytoskeleton of 15-day chick embryonic comeal epithelial cells have been studied using interference reflection microscopy (IRM), electron microscopy and fluorescent staining with specific antibodies against actin, tubulin, prekeratin, fibronectin and laminin In vivo, desmosomes were the most frequent intercellular junctions and hemidesmosomes were prominent at the basal surfac...

Endoblast and hypoblast tissue, dissected from early chick embryos, was explanted and cultured on glass or plastic substrata. These tissues grew rapidly to form epithelial sheets. Under the same conditions, mesoderm, dissected without the aid of dissociating agents, grew poorly. After 24 h in culture, the mesoderm explants consisted of a sparse outgrowth of fibroblast-like cells. When pieces of...

Echinoderms attach strongly and temporarily to the substratum by means of specialized organs, the podia or tube feet. The latter consist of a basal extensible cylinder, the stem, which bears an apical flattened disc. The disc repeatedly attaches to and detaches from the substratum through adhesive and de-adhesive secretions. In their activities, echinoderms have to cope with substrata of varyin...

BACKGROUND The economic impact of therapeutic non-adherence in chronic diseases has rarely been examined using qualitative standards for economic evaluation. This study illustrates the impact of non-adherence on the cost utility of renal transplantation versus haemodialysis from the societal perspective and examines the scope for adherence-enhancing interventions. METHODS Long-term costs and ...

OBJECTIVE To explore how a group of Swedish general practitioners (GPs) manage patients with a sore throat in relation to current guidelines as expressed in interviews. DESIGN Qualitative content analysis was used to analyse semi-structured interviews. SETTING Swedish primary care. SUBJECTS A strategic sample of 25 GPs. MAIN OUTCOME MEASURES Perceived management of sore throat patients....

Abstract Introduction The prevalence of obstructive sleep apnea (OSA) is high in patients with systolic heart failure (HFrEF) and has been associated poor prognosis this patient population. impact positive airway pressure (PAP) therapy OSA HFrEF remains unclear. This retrospective study sought to investigate the association between 1-year adherence PAP healthcare resource utilization (HCRU) new...