The genomic alterations for benign thyroid nodule, especially adenomatoid nodule, one of the most common types of hyperplasia lesion, are ill-studied. Here, we show whole-exome sequencing and/or transcriptome sequencing data on adenomatoid nodules with or without coincidental papillary thyroid carcinoma (PTC). Somatic mutation of BRAF (22/32) is only detected in PTC, while mutations in SPOP (4/...

Adenomatoid odontogenic tumor (AOT) is a rare noninvasive odontogenic tumor that occurs mostly in the second decade of life. Based on its tooth association, AOT can be classified into three categories of follicular, extrafollicular, and peripheral types; the follicular classification is considered as the most common type of AOT. This study reported a large extrafollicular case of AOT in a 40-ye...

BACKGROUND Sequestration with associated cystic adenomatoid malformation is rare. A study was undertaken to determine whether pulmonary sequestration associated with congenital cystic adenomatoid malformation has a more favourable natural history than that of sequestration without associated cystic adenomatoid malformation. METHODS An outline of the postnatal work up leading to the management...

This report describes the surgical therapy, clinical course and morphological characteristics of an adenomatoid odontogenic tumor that developed in the maxilla of a 16-year-old patient. The cystic tumor filled the maxillary sinus and was removed with the retained tooth. Healing was uneventful and no local recurrence was observed during a two-year period of follow-up control. The tumor showed im...

Introduction: Calcifying epithelial odontogenic tumor (CEOT) is a rare benign, but locally infiltrating neoplasm which accounts for less than 1% of all other tumors. The often associated with impacted teeth and twice as prevalent in the mandible. Dentigerous cysts are developmental cysts, commonly manifesting second third decades life. A greater incidence men women ratio 1.6:1 61.4% or unerupte...