The presence of ≥ 15% bone marrow (BM) ring sideroblasts (RS) and < 5% blasts is required for a diagnosis of refractory anemia with ring sideroblasts. We examined the phenotypic and prognostic relevance of this "15%" RS threshold in 200 patients with myelodysplastic syndromes (MDS) without excess blasts and with ≥ 1% RS. The impact of RS% was assessed both as a continuous and categorical variab...

Eduardo Maffini da Rosa1,2,3,4, Bruno Garcia Restelatto1, Verônica Poyer1 Universidade de Caxias do Sul, RS, Brazil1; Instituto de Cardiologia do RS Fundação Universitária de Cardiologia, IC-FUC, Brazil2; Instituto de Pesquisa Clínica para Estudos Multicêntricos (IPCEM) do CECS-UCS, RS, Brazil3; Liga Acadêmica de Estudos e Ações em Cardiologia da Universidade de Caxias do Sul4, Caxias do Sul, R...

A number of splicing factors contain extensive regions that are rich in arginine and serine (RS domains). These domains are thought to facilitate protein-protein interactions that are critical in the regulation of alternative splicing. Using a domain swap strategy, we have tested the ability of RS domains from several proteins to substitute in vivo for an essential RS domain in the Drosophila s...

An online recommendation system (RS) involves using information technology and customer information to tailor electronic commerce interactions between a business and individual customers. Extant information systems (IS) studies on RS have approached the phenomenon from many different perspectives, and our understanding of the nature and impacts of RS is fragmented. The current study reviews and...

Serotonin 2c receptors (5-HT2c-Rs) are drug targets for certain mental disorders, including schizophrenia, depression, and anxiety. 5-HT2c-Rs are expressed throughout the brain, making it difficult to link behavioral changes to circuit specific receptor expression. Various 5-HT-Rs, including 5-HT2c-Rs, are found in the dorsal raphe nucleus (DRN); however, the function of 5-HT2c-Rs and their inf...

To determine whether reduced nerve growth factor (NGF) and/or its high affinity receptor, trkA, play a role in the pathophysiology of Rett syndrome (RS), we used immunohistochemistry in paraffin-embedded human autopsy brain tissue, to quantify NGF and trkA levels within the frontal cortex of 9 RS females and 10 female controls of similar age. The results showed a significant reduction of NGF ex...

PURPOSE To measure vitreous levels of soluble TNF-receptors (sTNF-Rs) types I and II in eyes with rhegmatogenous retinal detachment (RRD), uncomplicated or complicated with proliferative vitreoretinopathy (PVR), and in eyes with proliferative diabetic retinopathy (PDR). To examine whether there is any relationship between vitreous levels of sTNF-Rs and clinical features of these conditions and ...

—In this paper, we demonstrate the higher hardware ef ciency of Reed-Solomon (RS) parallel turbo decoding compared with BCH parallel turbo decoding. Based on an innovative architecture, this is the rst implementation of fully parallel RS turbo decoder. A performance analysis is performed showing that RS Block Turbo Codes (RS-BTC) have decoding performance equivalent to Bose Ray-Chaudhuri Hocque...

Changes in human lifestyle and food consumption have resulted in a large increase in the incidence of type-2 diabetes, obesity, and colon disease, especially in Asia. These conditions are a growing threat to human health, but consumption of foods high in resistant starch (RS) can potentially reduce their incidence. Strategies to increase RS in rice are limited by a lack of knowledge of its mole...

This study was carried out at the Schizophrenia Program at Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil. * Dietitian. Specialist in Clinical Nutrition. MSc. student, Graduate Program in Psychiatry, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. ** Dietitian. Specialist in Public Health. MSc. in Medicine: Psychiatry, UFRGS, Porto Alegre, RS,...