Our prior research has shown that environmental enrichment (i.e. rats reared in an environment with novel objects, social contact with conspecifics) produces a protective antidepressant-like phenotype in rats and decreases neurobiological effects of acute psychological stress. Although CREB activity has been identified as a major player, the downstream molecular mechanisms remain largely unexpl...

The present study was designed to investigate the effect of acute heat stress on some hematological parameters in which young and adult Murrah buffaloes (n=6) were exposed to 40°C, 42°C, 45°C for 4 h duration in climatic chamber and thermoneutral temperature (22°C). Blood samples were collected by jugular vein puncture in sterile vacutainer tubes containing ethylene diamine tetra acetic acid (E...

High ambient temperatures have severe adverse effects on biological functions of high-yielding dairy cows. The metabolic adaption to heat stress was examined in 14 German Holsteins transition cows assigned to two groups, one heat-stressed (HS) and one pair-fed (PF) at the level of HS. After 6 days of thermoneutrality and ad libitum feeding (P1), cows were challenged for 6 days (P2) by heat stre...

Methamphetamine (METH) abuse continues to be a worldwide problem, damaging the myocardial tissues, as well as the brains of individual users. In addition, stressors that increase drug cravings also contribute to cardiovascular diseases. The aim of the present study was to examine the myocardial effects of METH, including METH‑stress interactions and particularly, the effect of METH RNA expressi...

Endothelial dysfunction is associated with increased cardiovascular mortality and morbidity; however, this dysfunction may be ameliorated by several therapies. For example, it has been reported that heat-induced increases in blood flow and shear stress enhance endothelium-mediated vasodilator function. Under these backgrounds, we expect that carbon dioxide (CO2)-rich water-induced increase in s...

AIMS To review the thermal effects of MDMA in humans, and discuss the practical implications. METHODS The literature on Ecstasy/MDMA, body temperature, and subjective thermal self-ratings was reviewed, and explanatory models for the changes in thermal homeostasis were examined and debated. RESULTS In human placebo-controlled laboratory studies, the effects of MDMA were dose related. Low dos...

the effects of dietary supplementation of grape seed extract (gse) and vitamin c on carcass characteristics, gut morphology and ileal microflora in broiler chickens exposed to chronic heat stress were examined. experimental diets included a control diet (without additive), 3 levels of gse (150, 300, 450 mg/kg of diet), and vitamin c (300 mg/kg of diet). each of the five diets was fed to 5 repli...

Stress activates multiple neural and endocrine systems to allow an animal to respond to and survive in a threatening environment. The corticotropin-releasing factor system is a primary initiator of this integrated response, which includes activation of the sympathetic nervous system and the hypothalamic-pituitary-adrenal (HPA) axis. The energetic response to acute stress is determined by the na...

maize improvement for high temperature tolerance requires the reliable assessment of parental inbred lines and their combinations. fifteen maize inbred lines were evaluated during 2007 and 2008 in shushtar city (khuzestan province). the inbred lines were planted at two dates: 6 july, to coincide heat stress with pollination time; and 27 july, as normal planting to avoid high temperature during ...