The plant family Rutaceae is known [1, 2] to be a prolific source of furoquinoline and pyranoquinoline alkaloids. Along with them acridine alka­ loids [3, 4] have also been isolated from several members of the same plant family. Recently furanfused acridine systems such as 1 l-methylfuro(2,3-c)acridan-6(l lH)one (1) have also been reported [5-7] to occur in some rutaceous plants. Typical exampl...

1,8-dioxo-decahydroacridines have been synthesized by the three-component reaction of aromatic aldehydes, aromatic amines (or ammonium acetate), and dimedone in the presence of sulfonic acid functionalized nanoporous silica (sba-pr-so3h) under solvent-free conditions. excellent yields, short reaction times, mild reaction conditions, and easy work-up procedures are advantages of this green method.

brucellosis is one of the most common zoonotic diseases in iran and human brucellosis is endemic in all parts of the country. growth of brucella is slow and blood culture of these bacteria by use of classical methods is time-consuming. furthermore, in endemic area culture is required for definitive diagnosis. in the present study, direct urease test and acridine orange staining were tried on th...

Supercritical carbon dioxide has gained increasing attention in food and pharmaceutical processing owing to the fact that it is environmentally inexpensive, not flammable, essentially non-toxic, and it has a convenient critical point. Also, it has been attracting much attention in many fields, such as extraction of sensitive materials and pharmaceutical processing and polymerization processes. ...

are heterogeneous with respect to molecular weight, buoyant density, and thermal stability. This finding constitutes evidence against unique points of breakage during DNA isolation. The variation in buoyant density suggests a local compositional heterogeneity in the chromosomal region of certain markers. The variation in molecular weight provides an explanation for the results of certain transf...

The mol-ecules in the crystal structure of the title compound, C(20)H(15)NO(2), form inversion dimers connected through the C-H⋯N and π-π inter-actions. These dimers are further linked by C-H⋯π inter-actions. The meth-oxy group is nearly coplanar with the acridine ring system [dihedral angle = 4.5 (1)°], whereas the phen-oxy fragment is nearly perpendicular to it [dihedral angle = 85.0 (1)°]. T...

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In the mol-ecule of the title compound, C(21)H(19)NO, the terminal saturated six-membered ring of the dihydro-acridine unit adopts an envelope conformation, while the other two fused rings are nearly coplanar, with a dihedral angle of 2.61 (3)°. The coplanar ring system is oriented with respect to the phenyl ring at a dihedral angle of 74.58 (3)°. In the crystal structure, there is a C-H⋯π cont...