OBJECTIVES To analyze the relative frequencies of various epileptic seizures and to study the age at onset of different seizure types in Nepalese children. DESIGN Prospective study. SETTING Hospital outpatient based in Kathmandu, Nepal, between November 2001 to October 2002. PARTICIPANTS 50 children diagnosed as epilepsy excluding neonatal and febrile seizures. MAIN OUTCOME MEASURE Diag...

A long-term follow-up study of Lennox-Gastaut syndrome (LGS) ( > 10 years) was conducted with 38 patients with severe motor and intellectual disabilities (SMID) to clarify the relationship between the rapid development of dysphagia and epileptic seizures, and to elucidate the long-term evolution of LGS in patients with SMID. Those who showed a relatively favourable seizure outcome were compared...

Voltage-gated calcium channels are key components in the etiology and pathogenesis of epilepsies. Former studies mainly focused on P/Q-type Ca(v)2.1 and T-type Ca(v)3.2 Ca(2+) channels involved in absence epileptogenesis, but recent findings also point to an intriguing role of the Ca(v)2.3 E/R-type Ca(2+) channel in ictogenesis and seizure propagation. Based on the observation that Ca(v)2.3 is ...

ICTAL FUNCTIONAL NEUROIMAGING OF CHILDHOOD ABSENCE EPILEPSY Matthew Vestal (Sponsored by Hal Blumenfeld). Departments of Neurology, Neurobiology, and Neurosurgery, Yale University School of Medicine, New Haven, CT. Absence seizures in Childhood Absence Epilepsy (CAE) are 5 – 10 second episodes of impaired consciousness that are characterized on electroencephalography (EEG) by frontally-predomin...

how to cite this article: fallah r, tirandazi f, ferdosian f, fadavi n. iron deficiency and iron deficiency anemia in children with first attack of seizure and on healthy control group : a comparative study. iran j child neurol. 2014 summer;8(3): 18-23.   abstract objective seizures are the most common pediatric neurologic problem. research of the association between iron deficiency and seizure...

The differentiation of frontal lobe epilepsy (FLE) and temporal lobe epilepsy (TLE) is a clinical problem of major theoretical and practical importance. Current electroclinical classification is based on retrospective studies of highly selected patients. When applied to the presurgical evaluation of patients, it has poor specificity. The current study adopts a different and prospective approach...

A series of new clubbed aryl oxadiazole-1,2,4-triazine derivatives (6a-l) were designed and synthesized using appropriate chemical routes. The structures to have the required structural elements for any compounds be potential anticonvulsant. Preliminary screening anticonvulsant activity was performed maximal electroshock seizure (MES), subcutaneous pentylenetetrazole-induced (scPTZ) behavioral ...