objectives: myelodysplastic syndromes (mdss) include a diverse group of clonal bone marrow disorders characterized by ineffective hematopoiesis and pancytopenia. it was found that down regulation of apaf1 , a putative tumor suppressor gene, leads to resistance to chemotherapy and disease development in some cancers. in this study, we investigated the relation of apaf1 methylation status with it...

introduction: measurement of diabetes management effectiveness includes the process of care and its quality, health outcome and response to care before everything; it needs a conceptual framework about this universal disease. minimum data set (mds) of diabetes make this framework by using standard data element with unique definition and effectiveness indicators preparation of diabetes managemen...

The distribution of lumber strength any grade may evolve, for example, due to climate change, forest fire, changes in processing methods, and other factors. So, North America the products industry monitors evolution their means, percentiles, or parameters ensure wood meet industrial standard. For administrative convenience informativeness, one adopt a rotating sampling plan by 36 mills initial ...

We present a method to obtain stateand time-dependent importance sampling estimators by repeatedly solving a minimum cross-entropy (MCE) program as the simulation progresses. This MCE-based approach lends a foundation to the natural notion to stop changing the measure when it is no longer needed. We use this method to obtain a stateand time-dependent estimator for the one-tailed probability of ...