Major types of internal can coatings used for food and beverages are made from synthetic polymers known as epoxy-based resins, mainly based on bisphenol A diglycidyl ether (BADGE). The migration components to is a concern safety. multiresidue method was developed the identification quantification six bisphenols, BADGE its derivatives, cyclo-di-BADGE in sixteen canned samples HPLC-FLD. showed ex...

Amphiphilic poly(ethylene oxide)–poly(propylene oxide) (PEO–PPO)-based copolymers are thermoresponsive materials having aggregation properties in aqueous medium. As hydrosolubilizers of poorly water-soluble drugs and improved stability of sensitive agents, these materials have been investigated for improvement in solubility, stability, release and bioavailability of drugs. The goal of the prese...

Nanoscale micelles as an effective drug delivery system have attracted increasing interest in malignancy therapy. The present study reported the construction of the cholesterol-enhanced doxorubicin (DOX)-loaded poly(D-lactide)-based micelle (CDM/DOX), poly(L-lactide)-based micelle (CLM/DOX), and stereocomplex micelle (CSCM/DOX) from the equimolar enantiomeric 4-armed poly(ethylene glycol)-polyl...

The Me₂Si-bridged ansa-Cp/amido half-metallocene, [Me₂Si(η⁵-Me₄C₅)(NtBu)]TiCl₂, termed a "constrained-geometry catalyst (CGC)", is a representative homogeneous Ziegler catalyst. CGC derivatives with the [1,2]azasilinane framework, in which the amide alkyl substituent is joined by the Si-bridge, were prepared, and the catalytic performances of these species was studied. Me₄C₅HSi(Me)(CH₂CH=CH₂)-N...