AIM To evaluate the genetic instability of 11 fertile and 25 infertile men. METHODS The methodology of sister chromatid exchanges (SCEs) was applied to cultures of peripheral blood lymphocytes, and the levels of SCEss were analyzed as a quantitative index of genotoxicity, along with the values of the mitotic index (MI) and the proliferation rate index (PRI) as qualitative indices of cytotoxic...

BACKGROUND Anogenital distance (AGD), a sexually dimorphic measure of genital development, is a marker for endocrine disruption in animal studies and may be shorter in infant males with genital anomalies. Given the correlation between anogenital distance and genital development, we sought to determine if anogenital distance varied in fertile compared to infertile adult men. METHODS A cross se...

INTRODUCTION The increased prevalence of upper normal limit of TSH and raised anti-thyroperoxidase antibody titer indicate, relatively more frequent occurrence of compensated thyroid function in infertile women. This finding necessitates considering such cases for a thorough investigation of pituitary-thyroid axis. In addition, as some patients may exhibit the clinical picture of hypothyroidism...

background: nowadays, chlamydia trachomatis is known as a causative agent of infertility. because of, asymptomatic nature of infection, many may suffer from its lasting complications such as infertility. this study was performed in tehran during april 2007 to april 2008 to compare the prevalence of chlamydia trachomatis infection in fertile and infertile women using elisa and pcr methods. metho...

BACKGROUND Thrombophilia-related mutations, such as coagulation factor V Leiden and factor II (G20210A), have been associated with female infertility due to spontaneous abortions during pregnancy. The possible role of mutations of these two factors in male infertility has not been studied to date. MATERIALS AND METHODS A total of 208 unrelated Greek men were investigated, including 108 infert...

The objective of the present study was to assess the ascorbic acid (AA) levels in seminal plasma of the fertile and infertile men and to investigate its relationship with sperm count, motility and normal morphology. Semen samples were provided by fertile [smoker (n = 25), nonsmoker (n = 21)] and infertile men [smoker (n = 23), nonsmoker (n = 32)]. A simplified method of reverse phase high perfo...

In the ovary, Anti-Mulllerian hormone (AMH) is produced by the granulosa cells of early developing follicles. The aim of our study was to assess the value of the AMH as a test to predict ovarian damage in groups of infertile women. Ninety seven infertile women were divided into four groups: (G1=29) with regular menstrual cycle, (G2=30) with prolonged or irregular cycles, (G3=21) with secondary ...

INTRODUCTION The exact causes of the decline in semen quality are not yet known, environmental factors have been considered to play an important role. Lead (Pb) and Cadmium (Cd) are two of the well-known reproductive toxicants to which humans are exposed occupationally and environmentally and can lead to negative effects on the testicular functions. The aim of this study was to evaluate lead an...