نتایج جستجو برای: 963

تعداد نتایج: 1023  

2012
Andrew McPherson Chunxiao Wu Alexander Wyatt Sohrab Shah Colin Collins S. Cenk Sahinalp

Complex Genomic Rearrangements (CGRs) are emerging as a new feature of cancer genomes. CGRs are characterized by multiple genomic breakpoints, and thus have the potential to simultaneously affect multiple genes, fusing some genes and interrupting other genes. Analysis of high-throughput whole genome shotgun sequencing (WGSS) is beginning to facilitate the discovery and characterization of CGRs,...

Journal: :Chemical research in toxicology 2002
Hao Chen John Shockcor Weiqi Chen Robert Espina Liang-Shang Gan A E Mutlib

The metabolic activation of (S)-5,6-difluoro-4-cyclopropylethynyl-4-trifluoromethyl-3,4-dihydro-2(1H)-quinazolinone, DPC 963, in rats was investigated by identifying and characterizing the GSH and mercapturic acid conjugates excreted in the bile and urine, respectively. The structures of these adducts, which were unequivocally elucidated by LC/MS/MS and NMR experiments, revealed the existence o...

2017
Shu-Ching Ma Hsiu-Hung Wang Tsair-Wei Chien

BACKGROUND Workplace bullying has been measured in many studies to investigate mental health issues. None uses online computerized adaptive testing (CAT) with cutting points to report bully prevalence at workplace. OBJECTIVE To develop an online CAT to examine person being bullied and verify whether item response theory-based CAT can be applied online for nurses to measure exposure to workpla...

Journal: :Genome research 2012
Andrew McPherson Chunxiao Wu Alexander Wyatt Sohrab P. Shah Colin Collins Süleyman Cenk Sahinalp

Complex genomic rearrangements (CGRs) are emerging as a new feature of cancer genomes. CGRs are characterized by multiple genomic breakpoints and thus have the potential to simultaneously affect multiple genes, fusing some genes and interrupting other genes. Analysis of high-throughput whole-genome shotgun sequencing (WGSS) is beginning to facilitate the discovery and characterization of CGRs, ...

2017
Canyou Zhang Yunzhou Ruan Jun Cheng Fei Zhao Yinyin Xia Hui Zhang Ewan Wilkinson Mrinalini Das Jie Li Wei Chen Dongmei Hu Kathiresan Jeyashree Lixia Wang

OBJECTIVE To calculate the yield and cost per diagnosed tuberculosis (TB) case for three World Health Organization screening algorithms and one using the Chinese National TB program (NTP) TB suspect definitions, using data from a TB prevalence survey of people aged 65 years and over in China, 2013. METHODS This was an analytic study using data from the above survey. Risk groups were defined a...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه صنعتی امیرکبیر(پلی تکنیک تهران) - دانشکده مهندسی صنایع 1386

در این پایان نامه استراتژیهای بیمه سبد سهام در بازار سرمایه ایران پیاده سازی شده، عملکرد آنان در بازه زمانی سالهای 1371 الی 1386 در مقایسه با عملکرد استراتژی خرید و نگهداری و همچنین در مقایسه با یکدیگر مورد بررسی قرار گرفته، تاثیر عواملی چون هزینه معامله، دوره متوازن سازی و نحوه محاسبه نوسان پذیری بر عملکرد استراتژیهای بیمه سبد سهام تحلیل و شاخص خاص بیمه سبد سهام معرفی و استفاده شده است. نتایج ...

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