Seven 2,3-epoxy-1-phenyl-3-aryl-1-propanones were synthesized via epoxidation of the corresponding 1-phenyl-3-aryl-2-propen-1-ones with 30% aqueous hydrogen peroxide in 74-99% yields using benzyldimethyltetradecylammonium chloride as phase transfer catalyst under ultrasound irradiation.

Ni(acac)2 catalyzes the four-component connection reaction of trimethylaluminium (or diphenylzinc), isoprene, aromatic aldehydes and p-anisidine in this order and provides (E)-1-aryl-1-(p-methoxyphenyl)amino-3-methyl-3-hexenes (or (E)-1-aryl-1-(p-methoxyphenyl)amino-3-methyl-5-phenyl-3-pentenes) selectively in good yield.

Synthesis of 4-(N,N- dimethylamino)-3-aryl-3-butene-2-one, ethyl-5-aryl-4-oxo-4H-pyran-2-carboxylate, ethyl-5-aryl-4-pyridones-2-carboxylate and 5-aryl-3-cyano-5-methyl-2-pyridones (aryl=3-thienyl, 2-furyl) are described.

Continuing in our researches on the syntheses, reactivity, pharmacological/biological activities of heterocyclic compounds containing one or more nitrogen atoms we have examined some chemico-physical properties (1H and 13C NMR, electrochemical behavior, ESR) three series 2-aryl-5(or 6)-nitrobenzimidazoles (1–3) variously substituted 2-aryl ring. The behavior nitro group benzimidazole ring has b...

Title of Dissertation: DEVELOPMENT OF ARYL SILOXANE CROSSCOUPLING TECHNOLOGY AND ITS APPLICATION TO THE SYNTHESIS OF COLCHICINE AND ALLOCOLCHICINE DERIVATIVES William Michael Seganish, Doctor of Philosophy, 2005 Dissertation directed by: Professor Philip DeShong Department of Chemistry and Biochemistry One of the most versatile methods for the formation of aryl-aryl bonds is the palladium-catal...

1,4-Di-(1-Ar-o-carboran-2-yl)benzene (Ar = 3,5-bis(trifluoromethyl)phenyl (1), phenyl (2), 4-n-butylphenyl (3), 4-N,N-dimethylaniline (4)) compounds that are electronically modulated at the C1-position of o-carborane with the electron-withdrawing or -donating aryl groups were prepared and characterized. The X-ray crystal structures of 1, 3, and 4 reveal that the two aryl groups on the C1-carbor...

A palladium-mediated intramolecular aryl–aryl coupling reaction was applied to the total synthesis of bioactive natural products, graphislactone G (1), and palmariols (2) B (3), which possess an unusual chloro-subsutituent on 6H-dibenzo[b,d]pyran-6-one skeleton. Based transition state model reaction, mechanistic aspect for regioselectivity is also discussed.