t cells have been identified as key players in the pathogenesis of type 1 diabetes. however, the exact role of t-cell subpopulations in this pathway is presently unknown. the purpose of this study was to assess the expression pattern of two lineage-specifying transcription factors gata - 3 and t - bet , which are important in t helper type 1 (th1) and th2 cell development , respectively. gene e...

background: type 2 diabetes mellitus with hyperlipidemia is a common disease. conventional anti-hyperglycemic and anti-hyperlipidemic drugs have limited efficacies and important side effects, so that alternative agents are needed. previous studies suggest that fiber-free artichoke (cynara scolymus l.) leaf extract may have anti-hyperglycemic and anti-hypercholesterolemic effects in hypercholest...

objective(s):pentoxifylline is an immunomodulatory and anti-inflammatory agent and is used in vascular disorders. it has been shown that pentoxifylline inhibits proinflammatory [d1] cytokines production. the purpose of this study was to investigate the therapeutic effects of pentoxifylline on the treatment of autoimmune diabetes in mice. materials and methods: diabetes was induced by multiple l...

background: the prevalence of diabetes mellitus among iranian aged 25-64 estimated to be about 7.7%. the aim of current study was the assessment of socioeconomic status of diabetic patients and their complications. methods: a cross sectional study was conducted on type 2 diabetic patients with complications in four major teaching hospitals affiliated to tehran university of medical sciences (tu...

background and objective : carbapenems are therapeutic choice against infections caused by gram-negative bacilli including strains of acinetobacter baumannii. resistance to these antibiotics is mediated by efflux pumps, porins, pbps and ß-lactamases. the aim of this study was to determine the possibility of existence of mbls, oxas and ges-1 betalactamase genes among clinical isolates of acineto...

ramadan fasting is an important pillars of islam .although patients and children expected from fasting during ramadan, but every diabetic adolescents intends to fast should consult his diabetes management time, and intensive monitoring of blood glucose and urine ketones .close observation by endocrinologist, and weekly follow- up and highly individualized planning for each diabetic person is es...

background: considering that serum gamma-glutamyl transferase (ggt) activity could reflect several different processes relevant to diabetes pathogenesis and the increasing rate of type 2 diabetes worldwide, the aim of this study was to assess the association between serum ggt concentrations and glucose intolerance, in the first-degree relatives (fdr) of type 2 diabetic patients. methods: in thi...

the date palm fruit stalk borer is one of the most important pests of date palm in the world. biochemical properties of digestive proteases in oryctes elegans prell larvae were investigated in this research and optimal total proteolytic and trypsin activities were obtained at ph 9.0 and 11.0, respectively. activity staining of protease on sds-page showed one isoform. also, zymogram pattern of t...

in this paper‎, ‎making use of a new identity‎, ‎we establish new‎ ‎inequalities of ostrowski type for the class of preinvex functions and‎ ‎gave some midpoint type inequalities‎.

how to cite this article: tonekaboni sh. approach to npc disease. iran j child neurol. 2015 autumn;9:4(suppl.1): 7. pls see pdf.