BACKGROUND Intramedullary spinal cord tumors are rare but clinically significant entities. Resection is critical to prevent permanent neurological deficits. However, no studies have investigated the quality of life (QOL) benefit of resection in adults. OBJECTIVE To investigate QOL outcomes after intramedullary spinal cord tumors resection. METHODS A consecutive retrospective review of all p...

In this note we reconsider Sen’s entropy function analysis for 5D supergravity actions containing Chern-Simons terms. The apparent lack of gauge invariance is usually tackled via a 4D reduction. Here we motivate how a systematic 5D procedure also works. In doing so, it becomes important to identify the correct 5D charges. In particular, we perform explicit calculations for the black ring and 5D...

We consider 5-dimensional supersymmetric field theories where supersymmetry is broken by the Scherk-Schwarz mechanism (or, equivalently, by the F -term VEV of the radion). In such models, the radion effective potential is calculable in terms of the 5d gauge coupling, the UV cutoff of the 5d field theory, and the field content. We provide simple, explicit formulae for the leading part of the two...

The impact of the Parkinson's disease and its treatment on the patients' health-related quality of life can be estimated either by means of generic measures such as the european quality of Life-5 Dimensions (EQ-5D) or speci ̄c measures such as the 8-item Parkinson's disease questionnaire (PDQ-8). In clinical studies, PDQ-8 could be used in detriment of EQ-5D due to the lack of resources, time or...

BACKGROUND Information on health related quality of life (HR-QOL) can be integrated with other classical health status indicators and be used to assist policy makers in resource allocation decisions. For this reason instruments such as the SF-12 and EQ-5D have been widely proposed as assessment tools to monitor changes in HR-QOL in general populations and very recently in general practice setti...

This study aimed to assess health-related quality of life (HRQOL) of Heilongjiang adult populations by using the EuroQol five-dimension three-level (EQ-5D-3L) questionnaire and to identify factors associated with HRQOL. Data from the National Health Services Survey (NHSS) 2008 in Heilongjiang province were obtained. Results of EQ-5D-3L questionnaires completed by 11,523 adult respondents (18 ye...

We construct a supersymmetric version of instanton operators in fivedimensional Yang-Mills theories. This is possible by considering a five-dimensional generalization of the familiar four-dimensional topologically twisted theory, where the gauge configurations corresponding to instanton operators are supersymmetric.

OBJECTIVES This study responds to a request in the National Institute for Health and Care Excellence (NICE) guidance to assess the impact of using alternative sources of utility values, applied to multiple sclerosis (MS). METHODS Incremental cost-effectiveness ratios (ICERs) were calculated using utility values based on UK and Dutch values of EQ-5D, two UK mappings and one Dutch mapping of EQ...

BACKGROUND Studies comparing the measurement properties of EQ-5D 3L (3L) and EQ-5D 5L (5L) are limited to specific patient populations with small sample sizes. Using a general population sample, we compared 3L and 5L in terms of their measurement properties and association with number of chronic conditions, including multimorbidity--the concurrent occurrence of two or more chronic conditions. ...

BACKGROUND The aim of the present study was to estimate minimally important differences (MIDs) in EQ-5D and SF-6D indices and to explore the responsiveness of EQ-5D and SF-6D indices in stroke. METHODS We used observational longitudinal survey data of EQ-5D and SF-36 that were administered to stroke patients at baseline and at 10 months. A range of MIDs for both indexes was estimated using an...