Due to non-affordability of GnRH analogues (GnRHa), Medroxy Progesterone Acetate (MPA) is still used as a treatment option in girls with CPP in India. The aim here is to study the clinical features of girls with CPP in respect to the age at presentation, etiology and outcome as per the medication used for their treatment (GnRHa vs MPA). Retrospective study of 38 girls with CPP(19 idiopathic) tr...

BACKGROUND Turner syndrome accounts for 15-20% of childhood usage of growth hormone (GH) in the UK but final height benefit remains uncertain. The most effective strategy for oestrogen replacement is also unclear. METHODS Fifty eight girls who, at start of treatment, were of mean age 9.1 years and projected final height 142.2 cm were randomised to receive in year 1, either low dose ethinyloes...

purpose: to determine the prevalence and to describe the demographic pattern of congenital cataract surgery performed at a referral hospital in iran during four consecutive years with respect to sex inequality in receiving eye care. methods: all children aged 15 years or less who had undergone congenital cataract surgery between 2006 and 2009 in labbafinejad medical center were enrolled in this...

Predicting the onset of menstruation (menarche age) and measuring height, weight and Body Mass Index (BMI) are among the major health information. Due to the importance of this issue, the present study was conducted to determine the anthropometric indexes and their relationship with menarche age in female students of Sabzevar, Iran in 2010. This cross sectional descriptive study was conducted o...

The aim of this study was to evaluate and compare the changes in soft tissue profile related to treatment with Twin Block and Herbst appliances. Sixty Class II, division 1, mandibular retrognathic patients were divided into three groups. Forty patients were randomly allocated to one of two functional appliance treatment groups. The first group comprised 11 girls and 9 boys (mean age= 12.74 ± 1....

BACKGROUND In adult women, the circulating level of anti-Müllerian hormone (AMH) is a novel marker of ovarian function, as it reflects the number of remaining ovarian follicles. Therefore, AMH has gained widespread attention in fertility clinics, and a low AMH is believed to predict impaired fertility and imminent menopause. However, the natural course of circulating AMH levels during female ch...

OBJECTIVE Prepubertal estradiol equivalents have been inconsistently linked to age at thelarche; elucidating this relationship becomes relevant given the worldwide decline in the age of puberty onset. Thus, our aim is to assess whether prepubertal girls with higher serum levels of estradiol equivalents at age 7 have a greater risk of presenting early thelarche (ET). DESIGN Nested case-control...

Depression is characterized by sleep difficulties, but the extent to which subjective and objective sleep disturbances precede depression are unclear. This study was designed to examine perceptions of sleep quality in addition to actigraphy- and diary-measured sleep variables in healthy girls at low and high familial risk for major depressive disorder. Forty-four healthy daughters and their mot...