Peppermint leaves contain flavonoids, menthofuran, and other phenolic compounds that have antioxidant activity are believed to inhibit collagen degradation in the skin. This study investigated efficacy of a 5% peppermint leaf extract cream increasing transforming growth factor β (TGF-β) expression amount as indicators maintenance male Wistar rats' skin exposed UVB. Method A randomized post-test...

purpose previous studies have shown that physical activity improves learning and memory. present study was performed to determine the effects of short term and long term treadmill exercise on learning, memory consolidation and retrieval of passive avoidance learning in an animal model. methods in this study fifty male wistar rats with 3-4 months of age were randomly divided into five groups (n=...

menopause is one of the most critical periods of woman's life. with reducing of ovarian estrogen; women are more prone to psychological and physical symptoms. the present study aimed to investigate the effect of melatonin on the climacteric symptoms.the present double blind, placebo randomized controlled clinical trial was conducted on 240 menopausal women (40 - 60 years old) referring to the g...

producing soluble or cellular components is one of the main functions of immune system which immunes the body against any kinds of inflammation. the aim of the present study was to investigate the plasma level changes of il-17, crp, and cpk in male mice after 8 weeks of aerobic exercise and omega-3 consumption. for this purpose, 170 male mice (mean age of two months and mean weight of 35±1 g) w...

Oxidative damage is involved in age-related inflammatory reactions. The anti-oxidative effects of hydrogen-rich water suppress oxidative damage, which may aid in inhibiting age-related inflammatory reactions. We investigated the effects of drinking hydrogen-rich water on aging periodontal tissues in healthy rats. Four-month-old male Fischer 344 rats (n = 12) were divided into two groups: the ex...

objective(s): to determine the effect of different doses of caffeine on orthodontic tooth movement (otm) in rats. materials and methods: forty male 250-300 g sprague-dawley rats were randomly divided into four groups of ten animals each and received 0 (control), 1 g/l, 2 g/l and 3 g/l caffeine in tap water for 3 days. orthodontic appliances were ligated between the maxillary first molars and in...

objective: atorvastatin has the pleiotropic effects, including anti-inflammation and antioxidant. therefore, this study considered to examine the effects of atorvastatin on nf-қb expression, as a main transcription factor for expression of inflammatory cytokines, in hyperglycemia-induced nephropathy in rat. materials and methods: twenty four male wistar rats were randomly divided into four grou...