Executive Board, AAP mor appearance in young women. New Eng. J. Med., 284:878, 1971. 2. Greenwald, P., Barlow, J. J., Nasca, P. C., and Burnett, W. S. : Vaginal cancer after maternal treatment with synthetic estrogens. New Eng. J. Med., 285:390, 1971. 3. Herbst, A. L., Ulfelder, H., and Poskanzer, D. C.: Registry of clear-cell carcinoma of genital tract in young women. New Eng. J. Med., 285:407...

Because psychological aspects often are underscored in the generation of tinnitus, we assessed the neuropsychological status in our group of patients. We found an increased number of abnormal electronystagmography (ENG) recordings in tinnitus patients. The aim of this study was to compare the ENG outcome with the patients' neuropsychological status. We carried out the study on 69 subjects compl...

Background The use of biomarkers for diagnosis of Preeclampsia (PE), a life-threatening pregnancy disorder, could reduce serious complications of this disease. In this study, we investigated dysregulation of endoglin (Eng) expression and diagnostic accuracy of soluble endoglin (sEng) in PE patients. Methods For this case-control study, 26 mild and 15 severe preeclamptic women along with 20 no...

ii Acknowledgements I would like to acknowledge and thank my major professor Dr. Gerald LaHoste for his help in this project. I would also like to extend thanks to Dr. Laura Harrison and Dr. David Ruskin for all of their advice and help in the completion of this project. I would also like to say thank-you to everyone at UNO for making my years here very enjoyable and I wish everyone the best in...

To identify mutations that cause hereditary hemorrhagic telangiectasia (HHT, or Rendu-Osler-Weber syndrome), clinical evaluations and genetic studies were performed on 32 families. Linkage studies in four of eight families indicated an endoglin (ENG) gene mutation. ENG sequences of affected members of the four linked families and probands from the 24 small families were screened for mutations, ...

The solution to the canonical problem of a radiating infinitesimal electric dipole antenna that is centred in a multilayered, concentric metamaterial-based spherical shell system is presented. It is demonstrated that when this system is electrically small, a specifically designed homogenous and isotropic epsilon-negative (ENG) layer can function as a distributed matching element to the antenna ...

OBJECTIVE To determine if angiogenesis is altered in adult Endoglin heterozygous (Eng(+/-)) mice, the animal model for the vascular disorder hereditary hemorrhagic telangiectasia type 1 (HHT1). METHODS Primary cultures of endothelial cells were generated from Eng(+/-) and Eng(+/+) mice and analyzed for proliferation, migration, and ability to form capillary-like tubes. Endothelial cells deriv...

Endoglin (ENG), an ancillary receptor for several members of the transforming growth factor (TGF)-beta superfamily, has a well-studied role in endothelial function. Here, we report that endoglin also plays an important role early in development at the level of the hemangioblast, an embryonic progenitor of the hematopoietic and endothelial lineages. Eng(-/-), Eng(+/-) and Eng(+/+) mouse embryoni...