objective: growth differentiation factor 9b (gdf9b) is an oocyte-derived growth factor. this protein is essential for the development of ovarian follicles and acts mainly by binding to its receptor on the surface of granulosa cells. the effect of gdf9b on the growth of follicles in various developmental stages, particularly primordial and primary follicles, is unknown. thus the aim of this stud...

conclusions this case raises awareness on the lack of visualization of ureteral flux during conventional cystoscopic evaluation in patients with renal failure undergoing pelvic organ prolapse repair, while also emphasizing the importance of confirming ureteral patency via retrograde ureteral intubation when cystoscopy is non-diagnostic. background pelvic floor reconstruction can result in obstr...

diagnostic peritoneal lavage (dpl) is considered by many as the most important investigation for the early detection of intraperitoneal injury. the aim of this study is to assess the accuracy of dpl as a diagnostic method in evaluating abdominal trauma. a prospectively maintained database of all dpls performed in the past 36 months at sina hospital was analyzed. information relative to the type...

background: diazinon is an organophosphorous pesticide which widely found in municipal, agricultural, and urban storm water discharges. the present study was conducted to achieve lethal concentration (lc50) and behavioral changes of rutilus rutilus caspius and hypophthal-micthys molitrix after exposure to lethal concentration of diazinon. methods: the experiment was carried out in static condit...

background : guillain-barre syndrome is an unusual complication of hematopoietic stem cell transplantation but it is extremely rare after solid organ transplantation such as kidney or liver transplantation case report : a 48-year-old man, a case of kidney transplantation presented with generalized weakness in an ascending pattern. history and examination were compatible with the diagnosis of gu...

the present study is related to the histochemical investigations on the changes in the intensity of reactions of axons, acid and neutral mucopolysaccharides, biologically active macromolecules, particularly glycogen and protein component as well as alkaline phosphatase (alpase) and adenosine triphosphatase (atpase) in the cells lining the olfactory epithelium of catla catla . the intense reacti...

[no abstract available]

BACKGROUND Healthcare professionals have a crucial role in organ donation and transplantation processes. Their attitude toward organ donation can affect public opinion and the donation decision made by deceased donors' relatives. The objectives of the study were to analyze the attitude of medical and nursing personnel toward deceased organ donation in two hospitals in Rio de Janeiro, Brazil, an...

Acinus (Acn) is a nuclear protein that participates in the regulation of autophagy. Loss of Acn function prevents autophagy in starving cells. Conversely, Acn activation induces basal autophagy. This enhances the quality control functions of autophagy such as the removal of misfolded proteins, thereby reducing neurodegeneration and prolonging lifespan. Acn activity is enhanced by Akt1-mediated ...

MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently introduced an additional level of intricacy to our understanding of gene regulation. There are currently over 10,000 miRNAs that have been identified in a range of species including metazoa, mycetozoa, viridiplantae, and viruses, of which 940, to date, are found in humans. It is estimated that more than 60% of h...