AIM: To evaluate the multiple biomarkers of colorectal tumor and their potential usage in early diagnosis of colorectal cancers. METHODS: Multiple biomarkers (DNA contents, AgNOR, PCNA, p53, c-erbB-2) in 10 normal colorectal mucosae, 37 colorectal adenomas and 55 colorectal cancers were analyzed quantitatively in the computed processing imaging system. Discrimination patterns were employed to e...

BACKGROUND: Cyclooxygenase-2 (COX)-2 inhibitor (Celecoxib) is a non-steroidal antiinflammatory drug (NSAIDs) and over-expression of COX-2 protein and mRNA has been reported in various cancer tissues. Therefore, it has been suggested that COX-2 is related to carcinogenesis. METHODS: Twenty five albino rats were used .They were divided into 3 groups; group I (normal control) and group II and III ...

Background: The health risks of crack cocaine smoking on the oral mucosa has not been widely researched and documented. Objective: The purpose of this study was to analyze the proliferative activity of oral epithelial cells exposed to crack cocaine smoke using silver nucleolar organizer region (AgNOR) staining. Methods: Oral smears were collected from clinically normal-appearing buccal mucosa b...

background: the health risks of crack cocaine smoking on the oral mucosa has not been widely researched and documented. objective: the purpose of this study was to analyze the proliferative activity of oral epithelial cells exposed to crack cocaine smoke using silver nucleolar organizer region (agnor) staining. methods: oral smears were collected from clinically normal-appearing buccal mucosa b...

thirty cases of benign prostatic hyperplasia and 30 cases of prostatic adenocarcinoma were selected and stained by agnor (argyrophilic staining of the nucleolar organizer region) method. specimens were obtained by either prostatectomy (open!tijr) or needle biopsy of the prostate. in this study, the sections of prostatic adenocarcinoma were reviewed. 6 cases were diagnosed as well-differentiated...

Background: It is well known that tobacco smoke causes cellular proliferation and chronic obstructive pulmonary disease (COPD), but changes in buccal mucosa cells in smokers and COPD patients remains unknown. Aims: The aim of this study is twofold: (i) to assess the effect of smoking on cellular proliferative activity of buccal mucosa in healthy smokers and in smoking COPD patients (ii) to dete...

Aydınlatma, modern tavuk yetiştiriciliğinde, üreme, büyüme, vücut sıcaklığı, yem tüketimi ve sindirim olayları da dahil olmak üzere birçok fizyolojik süreci etkileyen metabolik olaylarda belirleyici rol oynayan önemli unsurlardan biridir. Aydınlatmaya bağlı olarak oluşan değişiklikler, sinir sistemi endokrin sistemin görev aldığı olaylar sonucu meydana gelmektedir. Purkinje hücreleri, merkezi s...