Journal:
:iranian journal of basic medical sciences
0
vida homayouni immunology department, faculty of medicine, isfahan university of medical sciences, isfahan, iran
mazdak ganjalikhani-hakemi immunology department, faculty of medicine, isfahan university of medical sciences, isfahan, iran
abbas rezaei immunology department, faculty of medicine, isfahan university of medical sciences, isfahan, iran
hossein khanahmad genetic department, faculty of medicine, isfahan university of medical sciences, isfahan, iran
mahdi behdani biotechnology research center, biotechnology department, venom & bio-therapeutics molecules lab, pasteur institute of iran, tehran, iran
fatemeh kazemi lomedasht biotechnology research center, biotechnology department, venom & bio-therapeutics molecules lab, pasteur institute of iran, tehran, iran
objective(s): as t-cell immunoglobulin and mucin domain 3 (tim-3) is an immune regulatory molecule; its blocking or stimulating could alter the pattern of immune response towards a desired condition. based on the unique features of nanobodies, we aimed to construct an anti-tim-3 nanobody as an appropriate tool for manipulating immune responses for future therapeutic purposes. materials and meth...
