نتایج جستجو برای: 27

تعداد نتایج: 157360  

Journal: :TED: Tecné, Episteme y Didaxis 2010

Journal: :The Classical Review 1908

2007
Robert M Plenge Chris Cotsapas Leela Davies Alkes L Price Paul I W de Bakker Julian Maller Itsik Pe’er Noel P Burtt Brendan Blumenstiel Matt DeFelice Melissa Parkin Rachel Barry Wendy Winslow Claire Healy Robert R Graham Benjamin M Neale Elena Izmailova Ronenn Roubenoff Alexander N Parker Roberta Glass Elizabeth W Karlson Nancy Maher David A Hafler David M Lee Michael F Seldin Elaine F Remmers Annette T Lee Leonid Padyukov Lars Alfredsson Jonathan Coblyn Michael E Weinblatt Stacey B Gabriel Shaun Purcell Lars Klareskog Peter K Gregersen Nancy A Shadick Mark J Daly David Altshuler

Robert M Plenge1–3, Chris Cotsapas1,3, Leela Davies1, Alkes L Price1,4, Paul I W de Bakker1,3,4, Julian Maller1,3, Itsik Pe’er5, Noel P Burtt1, Brendan Blumenstiel1, Matt DeFelice1, Melissa Parkin1, Rachel Barry1, Wendy Winslow1, Claire Healy1, Robert R Graham1,3, Benjamin M Neale1,3,6, Elena Izmailova7, Ronenn Roubenoff 7, Alexander N Parker7, Roberta Glass2, Elizabeth W Karlson2, Nancy Maher2...

2017
Young-Han Kim

1. Drawing balls without replacement (20 pts). Suppose that we have an urn containing one red ball and n − 1 white balls. Each time we draw a ball at random from the urn without replacement (so after the n-th drawing, there is no ball left in the urn). X i = 1 if the i-th ball is red, 0 otherwise.

2004
John L. Hall Matthew S. Taubman Jun Ye

For laser applications in which measurement precision is a key feature, frequency-stabilized lasers are preferred, if not essential. This observation was true in the gas laser days when the 10−6 fractional Doppler width set the uncertainty scale. Now we have diode-pumped solid state lasers with fractional tuning range approaching 10−2 or more, and laser diode systems with several percent tuning...

2008
LIN ZHAO MICHIKO WATANABE JUNN YANAGISAWA SHUNSUKE NAKAGAWA HAJIME OISHI TAKEO MINAGUCHI TOSHIHARU YASUGI

To determine how estrogens are involved in the growth of endometrial cancer with varying degrees of differentiation, we investigated the status of p72, a novel specific coactivator for estrogen receptor α (ERα) activation function-1 (AF-1), AIB1, a steroid receptor coactivator amplified in breast cancer 1, erbB-2, a receptor tyrosine kinase, and ERα in endometrial cancer. Gene expression of ERα...

2004
Stefan Dercon Tessa Bold Joachim De Weerdt Alula Pankhurst

A funeral is a costly occasion. This paper studies indigenous insurance institutions developed to cope with the high costs of funerals, based on evidence from rural areas in Tanzania and Ethiopia. These institutions are based on well-defined rules and regulations, often offering premium-based insurance for funeral expenses. Increasingly, they are also offering other forms of insurance and credi...

2012
Sumihisa Orita Seiji Ohtori Kazuhisa Takahashi

Pain derived from musculoskeletal disorders play a major role in the health profile of the general population (Badley et al., 1994). Generally, osteoporosis patients experience several kinds of pain, including LBP: pain derived from external injury such as from fractures of the compressed vertebrae or femoral neck, and pain from internal consequences of the osteoporotic state without injury, wh...

2011
Kate Ward

This review considers the definition of a healthy bone phenotype through the life course and the modulating effects of muscle function and nutrition. In particular, it will emphasise that optimal bone strength (and how that is regulated) is more important than simple measures of bone mass. The forces imposed on bone by muscle loading are the primary determinants of musculoskeletal health. Any f...

2015
Norikazu Matsunaga Naomi Kaneko Angelina Yukiko Staub Takeo Nakanishi Ken-ichi Nunoya Haruo Imawaka Ikumi Tamai

To quantitatively understand the events in the human liver, we modeled a hepatic disposition of bosentan and its three known metabolites (Ro 48-5033, Ro 47-8634, and Ro 64-1056) in sandwichcultured human hepatocytes based on the known metabolic pathway. In addition, the hepatotoxicity of Ro 47-8634 and Ro 64-1056 was investigated because bosentan is well known as a hepatotoxic drug. A model ill...

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