Vitamin C (ascorbic acid, AA) is indispensable for normal metabolism of all mammalian cells including pancreatic acinar cells (PACs). PACs obtain AA from their surroundings via transport across the cell membrane. Chronic alcohol exposure negatively affects body AA homeostasis; it also inhibits uptake of other micronutrients into PACs, but its effect on AA uptake is not clear. We examined this i...

The carboxyl terminus of apolipoprotein (apo) E is required for lipoprotein association and for tetramer formation. To correlate these roles with specific regions within the carboxyl terminus, a series of apoE3 variants with carboxyl-terminal truncations at residues 266, 244, 223, and 191 were expressed in Escherichia coli. As determined by gel permeation and sedimentation equilibrium centrifug...

Bone morphogenetic protein (BMP) 7 counteracts physiological epithelial-to-mesenchymal transition, a process that is indicative of epithelial plasticity in developmental stages. Because epithelial-to-mesenchymal transition and its reversed process mesenchymal-to-epithelial transition (MET) are also involved in cancer progression, we investigated whether BMP7 plays a role in WM-266-4 melanoma ce...

Photodissociation dynamics of iodoacetonitrile (ICH2CN) have been investigated at pump wavelengths of 266 and 304 nm using a photofragment ion image velocity mapping technique. At both wavelengths, the prompt C-I bond rupture takes place on the repulsive excited states to give I(2P3/2) and I*(2P1/2), and their speed and spatial distributions are simultaneously measured. The recoil anisotropy pa...

OBJECTIVE To establish normal reference values of induced sputum cytology in healthy children in southern China. METHODS During a period from January 2010 to December 2011, a total of 580 healthy children (5-16 years of age) were approached. A total of 266 children (137 boys and 129 girls) participated in the study. Sputum induction was carried out by using 5% hypertonic saline. Cell types in...

We have identiied the optical counterpart of the EUV transient source RE J1255+266 with a 18 magnitude blue star which has an unusual optical spectrum showing a blue continuum and broad Balmer absorption lines characteristic of a DA white dwarf, together with intense narrow H Balmer and He I lines in emission. Subsequent optical spectroscopy and photometry, together with near-IR photometry, dem...

ARTS (Sept4_i2) is a mitochondrial pro-apoptotic protein that functions as a tumor suppressor. Its expression is significantly reduced in leukemia and lymphoma patients. ARTS binds and inhibits XIAP (X-linked Inhibitor of Apoptosis protein) by interacting with its Bir3 domain. ARTS promotes degradation of XIAP through the proteasome pathway. By doing so, ARTS removes XIAP inhibition of caspases...

The aims of this study are to find out, how nurses differ regarding their professional identity in times Covid-19 and if different clusters also satisfaction with information needs. To get more insights work situation Covid-19, we asked about sources they use by whom feel supported, fear working Covid-19. We conducted a cross-sectional study. used online questionnaires. 266 Nurses Germany (N = ...

Recenzja książki:Janusz Mariański, Pluralizm społeczno-kulturowy jako megatrend a religijność i moralność. Studium socjologiczne Wyższa Szkoła Nauk Społecznych z siedzibą w Lublinie, Lublin 2022, ss. 266

A series of 98% deuterated DKDP crystals were grown in solutions with different pD values (2.9, 3.3, 3.8, and 4.3) using the rapid growth method. Samples cut along z-direction fourth-harmonic-generation (FHG) direction which contained both pyramidal prismatic regions. The nonlinear absorption (NLA) coefficient ? was obtained Z-scan method operated at FHG wavelength (266 nm) a picosecond Nd:YAG ...