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Robert Boyle maintained that proper natural philosophical knowledge should be generated through experiment and that the foundations of such knowledge were to be constituted by experimentally produced matters of fact. Thomas Hobbes disagreed. In Hobbes's view Boyle's procedures could never yield the degree of certainty requisite in any enterprise worthy of being called philosophical. This text i...
The cytoskeletal protein talin, which is thought to couple integrins to F-actin, contains three binding sites (VBS1-VBS3) for vinculin, a protein implicated in the negative regulation of cell motility and whose activity is modulated by an intramolecular interaction between the vinculin head (Vh) and vinculin tail (Vt) domains. In the present study we show that recombinant talin polypeptides con...
The article is a study of the peculiarities exemption from punishment for individuals who have made public calls to commit terrorist act. Specifically, it was established that act involves violent activities or violence carried out with intention instill fear, panic, threaten lives, health, and safety people, intimidate by using civilians as human shields armed means. Terrorist acts are usually...
The simultaneous application of chemical modification of primary amines and the insertion of a lgF probe have been used to detect the nature and physical properties of the amino group influencing a selected region of the active center of the enzyme aspartate aminotransferase. The enzyme, carbamylated at the NH,-terminal alanine (transaminase’, produced from cyanate-treated holoenzyme) or at the...
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