OBJECTIVES This trial studied the efficacy and safety of itraconazole and fluconazole in the prevention of invasive fungal infections in neutropenic patients with haematological malignancies. PATIENTS AND METHODS An 8 week, open-label, randomized, parallel-group, multicentre trial comparing itraconazole oral solution (2.5 mg/kg twice daily; N=248) with fluconazole oral solution or capsules (4...

BACKGROUND ST-246® is an antiviral, orally bioavailable small molecule in clinical development for treatment of orthopoxvirus infections. An intravenous (i.v.) formulation may be required for some hospitalized patients who are unable to take oral medication. An i.v. formulation has been evaluated in three species previously used in evaluation of both efficacy and toxicology of the oral formulat...

Introduction Initiation of antiretroviral therapy (ART) and co-trimoxazole preventive therapy (CPT) is recommended for tuberculosis (TB)/human immunodeficiency virus (HIV) co-infected patients to prevent opportunistic infection. The aim of this study was to assess the prevalence of HIV among TB patients and initiation of ART and provision of CPT for TB/HIV co-infected patients in Hawassa univer...

Reseña del libro: Jiménez Berrio, Felipe (2019): Estudio sociolingüístico léxico disponible de escolares navarros. Pamplona: EUNSA, Colección lingüística, n.º 16. 246 Páginas. ISBN: 978-84-313-3439-0.

Environmental inequities are ubiquitous; emerging data suggest they affect the distribution of skin disease. The CalEnviroScreen is a cumulative environmental inequity score based on environmental, health, and sociodemographic data, allowing for comparison across census tracts in California. Previously, we showed that short-term exposure to wildfire smoke can exacerbate atopic dermatitis (AD). ...